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PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.
Srinivas US, Tay NSC, Jaynes P, Anbuselvan A, Ramachandran GK, Wardyn JD, Hoppe MM, Hoang PM, Peng Y, Lim S, Lee MY, Peethala PC, An O, Shendre A, Tan BWQ, Jemimah S, Lakshmanan M, Hu L, Jakhar R, Sachaphibulkij K, Lim LHK, Pervaiz S, Crasta K, Yang H, Tan P, Liang C, Ho L, Khanchandani V, Kappei D, Yong WP, Tan DSP, Bordi M, Campello S, Tam WL, Frezza C, Jeyasekharan AD. Srinivas US, et al. Among authors: yong wp. Oncogene. 2022 Mar;41(13):1986-2002. doi: 10.1038/s41388-022-02219-8. Epub 2022 Mar 2. Oncogene. 2022. PMID: 35236967
An integrative approach identified genes associated with drug response in gastric cancer.
Zhou J, Yong WP, Yap CS, Vijayaraghavan A, Sinha RA, Singh BK, Xiu S, Manesh S, Ngo A, Lim A, Ang C, Xie C, Wong FY, Lin SJ, Wan WK, Tan IB, Flotow H, Tan P, Lim KH, Yen PM, Goh LK. Zhou J, et al. Among authors: yong wp. Carcinogenesis. 2015 Apr;36(4):441-51. doi: 10.1093/carcin/bgv014. Epub 2015 Mar 5. Carcinogenesis. 2015. PMID: 25742747
Translating gastric cancer genomics into targeted therapies.
Ang YL, Yong WP, Tan P. Ang YL, et al. Among authors: yong wp. Crit Rev Oncol Hematol. 2016 Apr;100:141-6. doi: 10.1016/j.critrevonc.2016.02.007. Epub 2016 Feb 18. Crit Rev Oncol Hematol. 2016. PMID: 26947813 Free article. Review.
Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma.
Huang B, Deng S, Loo SY, Datta A, Yap YL, Yan B, Ooi CH, Dinh TD, Zhuo J, Tochhawng L, Gopinadhan S, Jegadeesan T, Tan P, Salto-Tellez M, Yong WP, Soong R, Yeoh KG, Goh YC, Lobie PE, Yang H, Kumar AP, Maciver SK, So JB, Yap CT. Huang B, et al. Among authors: yong wp. Oncotarget. 2016 May 3;7(18):25391-407. doi: 10.18632/oncotarget.8603. Oncotarget. 2016. PMID: 27058427 Free PMC article.
CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer.
Roy RK, Hoppe MM, Srivastava S, Samanta A, Sharma N, Tan KT, Yang H, Voon DC, Pang B, Teh M, Murata-Kamiya N, Hatakeyama M, Chang YT, Yong WP, Ito Y, Ho KY, Tan P, Soong R, Koeffler PH, Yeoh KG, Jeyasekharan AD. Roy RK, et al. Among authors: yong wp. Oncotarget. 2016 Aug 23;7(34):55290-55301. doi: 10.18632/oncotarget.10528. Oncotarget. 2016. PMID: 27421133 Free PMC article.
Value of a molecular screening program to support clinical trial enrollment in Asian cancer patients: The Integrated Molecular Analysis of Cancer (IMAC) Study.
Heong V, Syn NL, Lee XW, Sapari NS, Koh XQ, Adam Isa ZF, Sy Lim J, Lim D, Pang B, Thian YL, Ng LK, Wong AL, Soo RA, Yong WP, Chee CE, Lee SC, Goh BC, Soong R, Tan DSP. Heong V, et al. Among authors: yong wp. Int J Cancer. 2018 May 1;142(9):1890-1900. doi: 10.1002/ijc.31091. Epub 2017 Oct 17. Int J Cancer. 2018. PMID: 28994108 Free article.
171 results