Westover KD - Search Results

1

ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis.

Ramirez NP, Lee J, Zheng Y, Li L, Dennis B, Chen D, Challa A, Planelles V, Westover KD, Alto NM, D'Orso I. Ramirez NP, et al. Among authors: westover kd. Nat Commun. 2022 Mar 1;13(1):1109. doi: 10.1038/s41467-022-28772-0. Nat Commun. 2022. PMID: 35232997 Free PMC article.

2

Rationale for RAS mutation-tailored therapies.

Montalvo SK, Li L, Westover KD. Montalvo SK, et al. Among authors: westover kd. Future Oncol. 2017 Feb;13(3):263-271. doi: 10.2217/fon-2016-0363. Epub 2016 Oct 12. Future Oncol. 2017. PMID: 27728979 Review.

3

KRAS G12C Drug Development: Discrimination between Switch II Pocket Configurations Using Hydrogen/Deuterium-Exchange Mass Spectrometry.

Lu J, Harrison RA, Li L, Zeng M, Gondi S, Scott D, Gray NS, Engen JR, Westover KD. Lu J, et al. Among authors: westover kd. Structure. 2017 Sep 5;25(9):1442-1448.e3. doi: 10.1016/j.str.2017.07.003. Epub 2017 Aug 3. Structure. 2017. PMID: 28781083 Free PMC article.

4

Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C.

Zeng M, Lu J, Li L, Feru F, Quan C, Gero TW, Ficarro SB, Xiong Y, Ambrogio C, Paranal RM, Catalano M, Shao J, Wong KK, Marto JA, Fischer ES, Jänne PA, Scott DA, Westover KD, Gray NS. Zeng M, et al. Among authors: westover kd. Cell Chem Biol. 2017 Aug 17;24(8):1005-1016.e3. doi: 10.1016/j.chembiol.2017.06.017. Epub 2017 Aug 3. Cell Chem Biol. 2017. PMID: 28781124 Free article.

5

GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRAS^P34R.

Bera AK, Lu J, Lu C, Li L, Gondi S, Yan W, Nelson A, Zhang G, Westover KD. Bera AK, et al. Among authors: westover kd. Birth Defects Res. 2020 Jun;112(10):708-717. doi: 10.1002/bdr2.1647. Epub 2020 Mar 18. Birth Defects Res. 2020. PMID: 32187889 Free PMC article.

6

KRAS^Q61H Preferentially Signals through MAPK in a RAF Dimer-Dependent Manner in Non-Small Cell Lung Cancer.

Zhou ZW, Ambrogio C, Bera AK, Li Q, Li XX, Li L, Son J, Gondi S, Li J, Campbell E, Jin H, Okoro JJ, Xu CX, Janne PA, Westover KD. Zhou ZW, et al. Among authors: westover kd. Cancer Res. 2020 Sep 1;80(17):3719-3731. doi: 10.1158/0008-5472.CAN-20-0448. Epub 2020 Jun 30. Cancer Res. 2020. PMID: 32605999 Free article.

7

A structural model of a Ras-Raf signalosome.

Mysore VP, Zhou ZW, Ambrogio C, Li L, Kapp JN, Lu C, Wang Q, Tucker MR, Okoro JJ, Nagy-Davidescu G, Bai X, Plückthun A, Jänne PA, Westover KD, Shan Y, Shaw DE. Mysore VP, et al. Among authors: westover kd. Nat Struct Mol Biol. 2021 Oct;28(10):847-857. doi: 10.1038/s41594-021-00667-6. Epub 2021 Oct 8. Nat Struct Mol Biol. 2021. PMID: 34625747 Free PMC article.

8

Therapeutic Targeting the Allosteric Cysteinome of RAS and Kinase Families.

Li L, Meyer C, Zhou ZW, Elmezayen A, Westover K. Li L, et al. J Mol Biol. 2022 Sep 15;434(17):167626. doi: 10.1016/j.jmb.2022.167626. Epub 2022 May 18. J Mol Biol. 2022. PMID: 35595166 Free PMC article. Review.

9

Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability.

Kopra K, Valtonen S, Mahran R, Kapp JN, Hassan N, Gillette W, Dennis B, Li L, Westover KD, Plückthun A, Härmä H. Kopra K, et al. Among authors: westover kd. Int J Mol Sci. 2022 Jun 26;23(13):7095. doi: 10.3390/ijms23137095. Int J Mol Sci. 2022. PMID: 35806100 Free PMC article.

10

LIMS-Kinase provides sensitive and generalizable label-free in vitro measurement of kinase activity using mass spectrometry.

Meyer C, McCoy M, Li L, Posner B, Westover KD. Meyer C, et al. Among authors: westover kd. Cell Rep Phys Sci. 2023 Oct 18;4(10):101599. doi: 10.1016/j.xcrp.2023.101599. Epub 2023 Sep 26. Cell Rep Phys Sci. 2023. PMID: 38213501 Free PMC article.

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