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Partial p53 reactivation is sufficient to induce cancer regression.
Klimovich B, Meyer L, Merle N, Neumann M, König AM, Ananikidis N, Keber CU, Elmshäuser S, Timofeev O, Stiewe T. Klimovich B, et al. Among authors: neumann m. J Exp Clin Cancer Res. 2022 Mar 2;41(1):80. doi: 10.1186/s13046-022-02269-6. J Exp Clin Cancer Res. 2022. PMID: 35232479 Free PMC article.
p53 partial loss-of-function mutations sensitize to chemotherapy.
Klimovich B, Merle N, Neumann M, Elmshäuser S, Nist A, Mernberger M, Kazdal D, Stenzinger A, Timofeev O, Stiewe T. Klimovich B, et al. Among authors: neumann m. Oncogene. 2022 Feb;41(7):1011-1023. doi: 10.1038/s41388-021-02141-5. Epub 2021 Dec 14. Oncogene. 2022. PMID: 34907344 Free PMC article.
Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase.
Merle N, Elmshäuser S, Strassheimer F, Wanzel M, König AM, Funk J, Neumann M, Kochhan K, Helmprobst F, Pagenstecher A, Nist A, Mernberger M, Schneider A, Braun T, Borggrefe T, Savai R, Timofeev O, Stiewe T. Merle N, et al. Among authors: neumann m. Mol Cancer. 2022 Oct 3;21(1):191. doi: 10.1186/s12943-022-01661-2. Mol Cancer. 2022. PMID: 36192757 Free PMC article.
Molecular subgroups of T-cell acute lymphoblastic leukemia in adults treated according to pediatric-based GMALL protocols.
Neumann M, Beder T, Bastian L, Hänzelmann S, Bultmann M, Wolgast N, Hartmann A, Trautmann H, Ortiz-Tanchez J, Schlee C, Schroeder M, Fransecky L, Vosberg S, Fiedler W, Alakel N, Heberling L, Kondakci M, Starck M, Schwartz S, Raffel S, Müller-Tidow C, Schneller F, Reichle A, Burmeister T, Greif PA, Brüggemann M, Gökbuget N, Baldus CD. Neumann M, et al. Leukemia. 2024 Jun;38(6):1213-1222. doi: 10.1038/s41375-024-02264-0. Epub 2024 May 14. Leukemia. 2024. PMID: 38744920
1,729 results