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Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability.
Fumagalli V, Venzin V, Di Lucia P, Moalli F, Ficht X, Ambrosi G, Giustini L, Andreata F, Grillo M, Magini D, Ravà M, Friedrich C, Fontenot JD, Bousso P, Gilmore SA, Khan S, Baca M, Vivier E, Gasteiger G, Kuka M, Guidotti LG, Iannacone M. Fumagalli V, et al. Among authors: gasteiger g. Sci Immunol. 2022 Feb 25;7(68):eabi6112. doi: 10.1126/sciimmunol.abi6112. Epub 2022 Feb 25. Sci Immunol. 2022. PMID: 35213210
An essential role for the IL-2 receptor in Treg cell function.
Chinen T, Kannan AK, Levine AG, Fan X, Klein U, Zheng Y, Gasteiger G, Feng Y, Fontenot JD, Rudensky AY. Chinen T, et al. Among authors: gasteiger g. Nat Immunol. 2016 Nov;17(11):1322-1333. doi: 10.1038/ni.3540. Epub 2016 Sep 5. Nat Immunol. 2016. PMID: 27595233 Free PMC article.
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors.
Zeis P, Lian M, Fan X, Herman JS, Hernandez DC, Gentek R, Elias S, Symowski C, Knöpper K, Peltokangas N, Friedrich C, Doucet-Ladeveze R, Kabat AM, Locksley RM, Voehringer D, Bajenoff M, Rudensky AY, Romagnani C, Grün D, Gasteiger G. Zeis P, et al. Among authors: gasteiger g. Immunity. 2020 Oct 13;53(4):775-792.e9. doi: 10.1016/j.immuni.2020.09.002. Epub 2020 Sep 30. Immunity. 2020. PMID: 33002412 Free PMC article.
Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells.
Wiedemann GM, Grassmann S, Lau CM, Rapp M, Villarino AV, Friedrich C, Gasteiger G, O'Shea JJ, Sun JC. Wiedemann GM, et al. Among authors: gasteiger g. Cell Rep. 2020 Dec 15;33(11):108498. doi: 10.1016/j.celrep.2020.108498. Cell Rep. 2020. PMID: 33326784 Free PMC article.
Effector differentiation downstream of lineage commitment in ILC1s is driven by Hobit across tissues.
Friedrich C, Taggenbrock RLRE, Doucet-Ladevèze R, Golda G, Moenius R, Arampatzi P, Kragten NAM, Kreymborg K, Gomez de Agüero M, Kastenmüller W, Saliba AE, Grün D, van Gisbergen KPJM, Gasteiger G. Friedrich C, et al. Among authors: gasteiger g. Nat Immunol. 2021 Oct;22(10):1256-1267. doi: 10.1038/s41590-021-01013-0. Epub 2021 Aug 30. Nat Immunol. 2021. PMID: 34462601 Free PMC article.
Embryonic and neonatal waves generate distinct populations of hepatic ILC1s.
Sparano C, Solís-Sayago D, Vijaykumar A, Rickenbach C, Vermeer M, Ingelfinger F, Litscher G, Fonseca A, Mussak C, Mayoux M, Friedrich C, Nombela-Arrieta C, Gasteiger G, Becher B, Tugues S. Sparano C, et al. Among authors: gasteiger g. Sci Immunol. 2022 Sep 2;7(75):eabo6641. doi: 10.1126/sciimmunol.abo6641. Epub 2022 Sep 2. Sci Immunol. 2022. PMID: 36054340
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