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Development and validation of LC-MS/MS methods for the simultaneous quantification of sofosbuvir and its major metabolite (GS-331007) in blood plasma and cerebrospinal and seminal fluid: Application to a pilot clinical trial with a focus on Zika.
Vilhena LS, de Azevedo da Silva AC, Dias da Silva DM, Pinto DP, Coelho EF, de Araújo JFGM, da Silveira GPE, Pereira HM, da Silva LSFV, Estrela Marins RCE, Bortolini RG, Souza TML, Dos Santos VGV, de Assis Nascimento V, Amendoeira FC, da Fonseca LB. Vilhena LS, et al. Among authors: dos santos vgv. Biomed Chromatogr. 2023 May;37(5):e5606. doi: 10.1002/bmc.5606. Epub 2023 Mar 5. Biomed Chromatogr. 2023. PMID: 36797051 Clinical Trial.
Sera of patients infected by earlier lineages of SARS-CoV-2 are capable to neutralize later emerged variants of concern.
Pauvolid-Corrêa A, Caetano BC, Machado AB, Ferreira MA, Valente N, Neves TK, Geraldo K, Motta F, Dos Santos VGV, Grinsztejn B, Siqueira MM, Resende PC. Pauvolid-Corrêa A, et al. Among authors: dos santos vgv. Biol Methods Protoc. 2022 Aug 22;7(1):bpac021. doi: 10.1093/biomethods/bpac021. eCollection 2022. Biol Methods Protoc. 2022. PMID: 36128169 Free PMC article.
Kidney function and daily emtricitabine/tenofovir disoproxil fumarate pre-exposure prophylaxis against HIV: results from the real-life multicentric demonstrative project PrEP Brazil.
Petruccelli KCS, Baía-da-Silva DC, Val F, Valões MS, Cubas-Vega N, Silva-Neto AV, Sampaio V, Alencar A, Pecoits-Filho R, Moreira RC, Cardoso SW, Moreira RI, Leite IC, Madruga JV, Kallas EG, Alencastro PR, Hoagland B, Grinsztejn B, Santos VGV, Lacerda MVG. Petruccelli KCS, et al. Among authors: santos vgv. AIDS Res Ther. 2022 Feb 24;19(1):12. doi: 10.1186/s12981-022-00437-4. AIDS Res Ther. 2022. PMID: 35209929 Free PMC article.
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
WHO Solidarity Trial Consortium; Pan H, Peto R, Henao-Restrepo AM, Preziosi MP, Sathiyamoorthy V, Abdool Karim Q, Alejandria MM, Hernández García C, Kieny MP, Malekzadeh R, Murthy S, Reddy KS, Roses Periago M, Abi Hanna P, Ader F, Al-Bader AM, Alhasawi A, Allum E, Alotaibi A, Alvarez-Moreno CA, Appadoo S, Asiri A, Aukrust P, Barratt-Due A, Bellani S, Branca M, Cappel-Porter HBC, Cerrato N, Chow TS, Como N, Eustace J, García PJ, Godbole S, Gotuzzo E, Griskevicius L, Hamra R, Hassan M, Hassany M, Hutton D, Irmansyah I, Jancoriene L, Kirwan J, Kumar S, Lennon P, Lopardo G, Lydon P, Magrini N, Maguire T, Manevska S, Manuel O, McGinty S, Medina MT, Mesa Rubio ML, Miranda-Montoya MC, Nel J, Nunes EP, Perola M, Portolés A, Rasmin MR, Raza A, Rees H, Reges PPS, Rogers CA, Salami K, Salvadori MI, Sinani N, Sterne JAC, Stevanovikj M, Tacconelli E, Tikkinen KAO, Trelle S, Zaid H, Røttingen JA, Swaminathan S. WHO Solidarity Trial Consortium, et al. N Engl J Med. 2021 Feb 11;384(6):497-511. doi: 10.1056/NEJMoa2023184. Epub 2020 Dec 2. N Engl J Med. 2021. PMID: 33264556 Free PMC article. Clinical Trial.
Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.
Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, Goicochea P, Casapía M, Guanira-Carranza JV, Ramirez-Cardich ME, Montoya-Herrera O, Fernández T, Veloso VG, Buchbinder SP, Chariyalertsak S, Schechter M, Bekker LG, Mayer KH, Kallás EG, Amico KR, Mulligan K, Bushman LR, Hance RJ, Ganoza C, Defechereux P, Postle B, Wang F, McConnell JJ, Zheng JH, Lee J, Rooney JF, Jaffe HS, Martinez AI, Burns DN, Glidden DV; iPrEx Study Team. Grant RM, et al. N Engl J Med. 2010 Dec 30;363(27):2587-99. doi: 10.1056/NEJMoa1011205. Epub 2010 Nov 23. N Engl J Med. 2010. PMID: 21091279 Free PMC article. Clinical Trial.