Pandey AV - Search Results

1

Synthesis and Structure-Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents.

Wróbel TM, Rogova O, Sharma K, Rojas Velazquez MN, Pandey AV, Jørgensen FS, Arendrup FS, Andersen KL, Björkling F. Wróbel TM, et al. Among authors: pandey av. Biomolecules. 2022 Jan 20;12(2):165. doi: 10.3390/biom12020165. Biomolecules. 2022. PMID: 35204665 Free PMC article.

2

Specificity of anti-prostate cancer CYP17A1 inhibitors on androgen biosynthesis.

Udhane SS, Dick B, Hu Q, Hartmann RW, Pandey AV. Udhane SS, et al. Among authors: pandey av. Biochem Biophys Res Commun. 2016 Sep 2;477(4):1005-1010. doi: 10.1016/j.bbrc.2016.07.019. Epub 2016 Jul 6. Biochem Biophys Res Commun. 2016. PMID: 27395338

3

CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2.

Malikova J, Brixius-Anderko S, Udhane SS, Parween S, Dick B, Bernhardt R, Pandey AV. Malikova J, et al. Among authors: pandey av. J Steroid Biochem Mol Biol. 2017 Nov;174:192-200. doi: 10.1016/j.jsbmb.2017.09.007. Epub 2017 Sep 8. J Steroid Biochem Mol Biol. 2017. PMID: 28893623

4

Variability in Loss of Multiple Enzyme Activities Due to the Human Genetic Variation P284T Located in the Flexible Hinge Region of NADPH Cytochrome P450 Oxidoreductase.

Parween S, Rojas Velazquez MN, Udhane SS, Kagawa N, Pandey AV. Parween S, et al. Among authors: pandey av. Front Pharmacol. 2019 Oct 15;10:1187. doi: 10.3389/fphar.2019.01187. eCollection 2019. Front Pharmacol. 2019. PMID: 31749697 Free PMC article.

5

Molecular Basis of CYP19A1 Deficiency in a 46,XX Patient With R550W Mutation in POR: Expanding the PORD Phenotype.

Parween S, Fernández-Cancio M, Benito-Sanz S, Camats N, Rojas Velazquez MN, López-Siguero JP, Udhane SS, Kagawa N, Flück CE, Audí L, Pandey AV. Parween S, et al. Among authors: pandey av. J Clin Endocrinol Metab. 2020 Apr 1;105(4):dgaa076. doi: 10.1210/clinem/dgaa076. J Clin Endocrinol Metab. 2020. PMID: 32060549 Free article.

6

Inhibition of placental CYP19A1 activity remains as a valid hypothesis for 46,XX virilization in P450 oxidoreductase deficiency.

Flück CE, Parween S, Rojas Velazquez MN, Pandey AV. Flück CE, et al. Among authors: pandey av. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):14632-14633. doi: 10.1073/pnas.2003154117. Epub 2020 Jun 23. Proc Natl Acad Sci U S A. 2020. PMID: 32576700 Free PMC article. No abstract available.

7

Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase.

Jensen SB, Thodberg S, Parween S, Moses ME, Hansen CC, Thomsen J, Sletfjerding MB, Knudsen C, Del Giudice R, Lund PM, Castaño PR, Bustamante YG, Velazquez MNR, Jørgensen FS, Pandey AV, Laursen T, Møller BL, Hatzakis NS. Jensen SB, et al. Among authors: pandey av. Nat Commun. 2021 Apr 15;12(1):2260. doi: 10.1038/s41467-021-22562-w. Nat Commun. 2021. PMID: 33859207 Free PMC article.

8

Loss of Protein Stability and Function Caused by P228L Variation in NADPH-Cytochrome P450 Reductase Linked to Lower Testosterone Levels.

Rojas Velazquez MN, Noebauer M, Pandey AV. Rojas Velazquez MN, et al. Among authors: pandey av. Int J Mol Sci. 2022 Sep 4;23(17):10141. doi: 10.3390/ijms231710141. Int J Mol Sci. 2022. PMID: 36077536 Free PMC article.

9

Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment.

Wróbel TM, Jørgensen FS, Pandey AV, Grudzińska A, Sharma K, Yakubu J, Björkling F. Wróbel TM, et al. Among authors: pandey av. J Med Chem. 2023 May 25;66(10):6542-6566. doi: 10.1021/acs.jmedchem.3c00442. Epub 2023 May 16. J Med Chem. 2023. PMID: 37191389 Free PMC article. Review.

10

Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis.

Wróbel TM, Sharma K, Mannella I, Oliaro-Bosso S, Nieckarz P, Du Toit T, Voegel CD, Rojas Velazquez MN, Yakubu J, Matveeva A, Therkelsen S, Jørgensen FS, Pandey AV, Pippione AC, Lolli ML, Boschi D, Björkling F. Wróbel TM, et al. Among authors: pandey av. Biomolecules. 2023 Sep 5;13(9):1349. doi: 10.3390/biom13091349. Biomolecules. 2023. PMID: 37759751 Free PMC article.

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