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Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease.
Braun T, Sosnovski KE, Amir A, BenShoshan M, VanDussen KL, Karns R, Levhar N, Abbas-Egbariya H, Hadar R, Efroni G, Castel D, Avivi C, Rosen MJ, Grifiths AM, Walters TD, Mack DR, Boyle BM, Ali SA, Moore SR, Schirmer M, Xavier RJ, Kugathasan S, Jegga AG, Weiss B, Mayer C, Barshack I, Ben-Horin S, Ulitsky I, Beucher A, Ferrer J, Hyams JS, Denson LA, Haberman Y. Braun T, et al. JCI Insight. 2023 Jul 24;8(14):e170181. doi: 10.1172/jci.insight.170181. JCI Insight. 2023. PMID: 37261910 Free PMC article.
pH regulates hematopoietic stem cell potential via polyamines.
Kumar S, Vassallo JD, Nattamai KJ, Hassan A, Karns R, Vollmer A, Soller K, Sakk V, Sacma M, Nemkov T, D'Alessandro A, Geiger H. Kumar S, et al. EMBO Rep. 2023 May 4;24(5):e55373. doi: 10.15252/embr.202255373. Epub 2023 Mar 21. EMBO Rep. 2023. PMID: 36943011 Free PMC article.
EZH2 is a key component of hepatoblastoma tumor cell growth.
Glaser K, Schepers EJ, Zwolshen HM, Lake CM, Timchenko NA, Karns RA, Cairo S, Geller JI, Tiao GM, Bondoc AJ. Glaser K, et al. Among authors: karns ra. Pediatr Blood Cancer. 2024 Feb;71(2):e30774. doi: 10.1002/pbc.30774. Epub 2023 Nov 21. Pediatr Blood Cancer. 2024. PMID: 37990130
Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.
Clarkston K, Karns R, Jegga AG, Sharma M, Fox S, Ojo BA, Minar P, Walters TD, Griffiths AM, Mack DR, Boyle B, LeLeiko NS, Markowitz J, Rosh JR, Patel AS, Shah S, Baldassano RN, Pfefferkorn M, Sauer C, Kugathasan S, Haberman Y, Hyams JS, Denson LA, Rosen MJ. Clarkston K, et al. J Crohns Colitis. 2022 Nov 23;16(11):1735-1750. doi: 10.1093/ecco-jcc/jjac075. J Crohns Colitis. 2022. PMID: 35665804 Free PMC article.
Type I interferons regulate susceptibility to inflammation-induced preterm birth.
Cappelletti M, Presicce P, Lawson MJ, Chaturvedi V, Stankiewicz TE, Vanoni S, Harley IT, McAlees JW, Giles DA, Moreno-Fernandez ME, Rueda CM, Senthamaraikannan P, Sun X, Karns R, Hoebe K, Janssen EM, Karp CL, Hildeman DA, Hogan SP, Kallapur SG, Chougnet CA, Way SS, Divanovic S. Cappelletti M, et al. JCI Insight. 2017 Mar 9;2(5):e91288. doi: 10.1172/jci.insight.91288. JCI Insight. 2017. PMID: 28289719 Free PMC article.
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.
Haberman Y, Tickle TL, Dexheimer PJ, Kim MO, Tang D, Karns R, Baldassano RN, Noe JD, Rosh J, Markowitz J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, Baker SS, Huttenhower C, Keljo DJ, Hyams JS, Kugathasan S, Walters TD, Aronow B, Xavier RJ, Gevers D, Denson LA. Haberman Y, et al. J Clin Invest. 2014 Aug;124(8):3617-33. doi: 10.1172/JCI75436. Epub 2014 Jul 8. J Clin Invest. 2014. PMID: 25003194 Free PMC article.
Corrigendum. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.
Haberman Y, Tickle TL, Dexheimer PJ, Kim MO, Tang D, Karns R, Baldassano RN, Noe JD, Rosh J, Markowitz J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, Baker SS, Huttenhower C, Keljo DJ, Hyams JS, Kugathasan S, Walters TD, Aronow B, Xavier RJ, Gevers D, Denson LA. Haberman Y, et al. J Clin Invest. 2015 Mar 2;125(3):1363. doi: 10.1172/JCI79657. Epub 2015 Mar 2. J Clin Invest. 2015. PMID: 25729854 Free PMC article. No abstract available.
Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice.
Miethke AG, Zhang W, Simmons J, Taylor AE, Shi T, Shanmukhappa SK, Karns R, White S, Jegga AG, Lages CS, Nkinin S, Keller BT, Setchell KD. Miethke AG, et al. Hepatology. 2016 Feb;63(2):512-23. doi: 10.1002/hep.27973. Epub 2015 Aug 21. Hepatology. 2016. PMID: 26172874 Free PMC article.
85 results