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TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.
Ma XR, Prudencio M, Koike Y, Vatsavayai SC, Kim G, Harbinski F, Briner A, Rodriguez CM, Guo C, Akiyama T, Schmidt HB, Cummings BB, Wyatt DW, Kurylo K, Miller G, Mekhoubad S, Sallee N, Mekonnen G, Ganser L, Rubien JD, Jansen-West K, Cook CN, Pickles S, Oskarsson B, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Shorter J, Myong S, Green EM, Seeley WW, Petrucelli L, Gitler AD. Ma XR, et al. Nature. 2022 Mar;603(7899):124-130. doi: 10.1038/s41586-022-04424-7. Epub 2022 Feb 23. Nature. 2022. PMID: 35197626 Free PMC article.
ALS Genetics: Gains, Losses, and Implications for Future Therapies.
Kim G, Gautier O, Tassoni-Tsuchida E, Ma XR, Gitler AD. Kim G, et al. Among authors: ma xr. Neuron. 2020 Dec 9;108(5):822-842. doi: 10.1016/j.neuron.2020.08.022. Epub 2020 Sep 14. Neuron. 2020. PMID: 32931756 Free PMC article. Review.
Convergence of coronary artery disease genes onto endothelial cell programs.
Schnitzler GR, Kang H, Fang S, Angom RS, Lee-Kim VS, Ma XR, Zhou R, Zeng T, Guo K, Taylor MS, Vellarikkal SK, Barry AE, Sias-Garcia O, Bloemendal A, Munson G, Guckelberger P, Nguyen TH, Bergman DT, Hinshaw S, Cheng N, Cleary B, Aragam K, Lander ES, Finucane HK, Mukhopadhyay D, Gupta RM, Engreitz JM. Schnitzler GR, et al. Among authors: ma xr. Nature. 2024 Feb;626(8000):799-807. doi: 10.1038/s41586-024-07022-x. Epub 2024 Feb 7. Nature. 2024. PMID: 38326615
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease.
Alugubelli YR, Xiao J, Khatua K, Kumar S, Sun L, Ma Y, Ma XR, Vulupala VR, Atla S, Blankenship LR, Coleman D, Xie X, Neuman BW, Liu WR, Xu S. Alugubelli YR, et al. Among authors: ma xr. J Med Chem. 2024 Apr 25;67(8):6495-6507. doi: 10.1021/acs.jmedchem.3c02416. Epub 2024 Apr 12. J Med Chem. 2024. PMID: 38608245 Free PMC article.
Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors.
Khatua K, Alugubelli YR, Yang KS, Vulupala VR, Blankenship LR, Coleman D, Atla S, Chaki SP, Geng ZZ, Ma XR, Xiao J, Chen PH, Cho CD, Sharma S, Vatansever EC, Ma Y, Yu G, Neuman BW, Xu S, Liu WR. Khatua K, et al. Among authors: ma xr. Antiviral Res. 2024 May;225:105874. doi: 10.1016/j.antiviral.2024.105874. Epub 2024 Mar 28. Antiviral Res. 2024. PMID: 38555023
147 results