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Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors.
Rullo M, La Spada G, Miniero DV, Gottinger A, Catto M, Delre P, Mastromarino M, Latronico T, Marchese S, Mangiatordi GF, Binda C, Linusson A, Liuzzi GM, Pisani L. Rullo M, et al. Among authors: latronico t. Eur J Med Chem. 2023 Jul 5;255:115352. doi: 10.1016/j.ejmech.2023.115352. Epub 2023 Apr 8. Eur J Med Chem. 2023. PMID: 37178666
Luminescent PLGA Nanoparticles for Delivery of Darunavir to the Brain and Inhibition of Matrix Metalloproteinase-9, a Relevant Therapeutic Target of HIV-Associated Neurological Disorders.
Latronico T, Rizzi F, Panniello A, Laquintana V, Arduino I, Denora N, Fanizza E, Milella S, Mastroianni CM, Striccoli M, Curri ML, Liuzzi GM, Depalo N. Latronico T, et al. ACS Chem Neurosci. 2021 Nov 17;12(22):4286-4301. doi: 10.1021/acschemneuro.1c00436. Epub 2021 Nov 2. ACS Chem Neurosci. 2021. PMID: 34726377 Free PMC article.
37 results