Musilek K - Search Results

1

Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides.

Kohoutova Z, Malinak D, Andrys R, Svobodova J, Psotka M, Schmidt M, Prchal L, Musilek K. Kohoutova Z, et al. Among authors: musilek k. J Enzyme Inhib Med Chem. 2022 Dec;37(1):760-767. doi: 10.1080/14756366.2022.2041628. J Enzyme Inhib Med Chem. 2022. PMID: 35193448 Free PMC article.

2

Effective bisquaternary reactivators of tabun-inhibited AChE.

Kuca K, Cabal J, Musilek K, Jun D, Bajgar J. Kuca K, et al. Among authors: musilek k. J Appl Toxicol. 2005 Nov-Dec;25(6):491-5. doi: 10.1002/jat.1084. J Appl Toxicol. 2005. PMID: 16092078

3

Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

Musilek K, Kuca K, Jun D, Dohnal V, Dolezal M. Musilek K, et al. Bioorg Med Chem Lett. 2006 Feb;16(3):622-7. doi: 10.1016/j.bmcl.2005.10.059. Epub 2005 Nov 8. Bioorg Med Chem Lett. 2006. PMID: 16288867

4

Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

Musilek K, Kuca K, Jun D, Dohnal V, Dolezal M. Musilek K, et al. J Enzyme Inhib Med Chem. 2005 Oct;20(5):409-15. doi: 10.1080/14756360500179762. J Enzyme Inhib Med Chem. 2005. PMID: 16335048

5

Structural requirements of acetylcholinesterase reactivators.

Kuca K, Juna D, Musilek K. Kuca K, et al. Among authors: musilek k. Mini Rev Med Chem. 2006 Mar;6(3):269-77. doi: 10.2174/138955706776073510. Mini Rev Med Chem. 2006. PMID: 16515465 Review.

6

Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Dolezal M. Musilek K, et al. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5673-6. doi: 10.1016/j.bmcl.2006.08.011. Epub 2006 Aug 24. Bioorg Med Chem Lett. 2006. PMID: 16934462

7

New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin.

Hrabinova M, Musilek K, Jun D, Kuca K. Hrabinova M, et al. Among authors: musilek k. J Enzyme Inhib Med Chem. 2006 Oct;21(5):515-9. doi: 10.1080/14756360600741420. J Enzyme Inhib Med Chem. 2006. PMID: 17194020

8

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M. Musilek K, et al. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3172-6. doi: 10.1016/j.bmcl.2007.03.025. Epub 2007 Mar 13. Bioorg Med Chem Lett. 2007. PMID: 17383875

9

In vitro reactivation potency of acetylcholinesterase reactivators--K074 and K075--to reactivate tabun-inhibited human brain cholinesterases.

Kuca K, Cabal J, Jun D, Musilek K. Kuca K, et al. Among authors: musilek k. Neurotox Res. 2007 Feb;11(2):101-6. doi: 10.1007/BF03033389. Neurotox Res. 2007. PMID: 17449453

10

Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.

Musilek K, Holas O, Jun D, Dohnal V, Gunn-Moore F, Opletalova V, Dolezal M, Kuca K. Musilek K, et al. Bioorg Med Chem. 2007 Nov 1;15(21):6733-41. doi: 10.1016/j.bmc.2007.08.002. Epub 2007 Aug 10. Bioorg Med Chem. 2007. PMID: 17764957

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