Ortmann BM - Search Results

1

The impact of hypoxia on B cells in COVID-19.

Kotagiri P, Mescia F, Hanson AL, Turner L, Bergamaschi L, Peñalver A, Richoz N, Moore SD, Ortmann BM, Dunmore BJ, Morgan MD, Tuong ZK; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Göttgens B, Toshner M, Hess C, Maxwell PH, Clatworthy MR, Nathan JA, Bradley JR, Lyons PA, Burrows N, Smith KGC. Kotagiri P, et al. Among authors: ortmann bm. EBioMedicine. 2022 Mar;77:103878. doi: 10.1016/j.ebiom.2022.103878. Epub 2022 Feb 19. EBioMedicine. 2022. PMID: 35189575 Free PMC article.

2

ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex.

Bailey PSJ, Ortmann BM, Martinelli AW, Houghton JW, Costa ASH, Burr SP, Antrobus R, Frezza C, Nathan JA. Bailey PSJ, et al. Among authors: ortmann bm. Nat Commun. 2020 Aug 13;11(1):4046. doi: 10.1038/s41467-020-17862-6. Nat Commun. 2020. PMID: 32792488 Free PMC article.

3

Genetic approaches to understand cellular responses to oxygen availability.

Ortmann BM, Nathan JA. Ortmann BM, et al. FEBS J. 2022 Sep;289(18):5396-5412. doi: 10.1111/febs.16072. Epub 2021 Jun 26. FEBS J. 2022. PMID: 34125486 Free article. Review.

4

The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes.

Ortmann BM, Burrows N, Lobb IT, Arnaiz E, Wit N, Bailey PSJ, Jordon LH, Lombardi O, Peñalver A, McCaffrey J, Seear R, Mole DR, Ratcliffe PJ, Maxwell PH, Nathan JA. Ortmann BM, et al. Nat Genet. 2021 Jul;53(7):1022-1035. doi: 10.1038/s41588-021-00887-y. Epub 2021 Jun 21. Nat Genet. 2021. PMID: 34155378 Free PMC article.

5

Hypoxia research, where to now?

Ortmann BM, Taylor CT, Rocha S. Ortmann BM, et al. Trends Biochem Sci. 2024 Apr 9:S0968-0004(24)00074-4. doi: 10.1016/j.tibs.2024.03.008. Online ahead of print. Trends Biochem Sci. 2024. PMID: 38599898 Free article. Review.

6

Cell cycle progression in response to oxygen levels.

Ortmann B, Druker J, Rocha S. Ortmann B, et al. Cell Mol Life Sci. 2014 Sep;71(18):3569-82. doi: 10.1007/s00018-014-1645-9. Epub 2014 May 25. Cell Mol Life Sci. 2014. PMID: 24858415 Free PMC article. Review.

7

PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia.

Mudie S, Bandarra D, Batie M, Biddlestone J, Moniz S, Ortmann B, Shmakova A, Rocha S. Mudie S, et al. Cell Cycle. 2014;13(24):3878-91. doi: 10.4161/15384101.2014.972889. Cell Cycle. 2014. PMID: 25558831 Free PMC article.

8

CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells.

Ortmann B, Bensaddek D, Carvalhal S, Moser SC, Mudie S, Griffis ER, Swedlow JR, Lamond AI, Rocha S. Ortmann B, et al. J Cell Sci. 2016 Jan 1;129(1):191-205. doi: 10.1242/jcs.179911. Epub 2015 Dec 7. J Cell Sci. 2016. PMID: 26644182 Free PMC article.

9

PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192.

Moser SC, Bensaddek D, Ortmann B, Maure JF, Mudie S, Blow JJ, Lamond AI, Swedlow JR, Rocha S. Moser SC, et al. Dev Cell. 2013 Aug 26;26(4):381-92. doi: 10.1016/j.devcel.2013.06.014. Epub 2013 Aug 8. Dev Cell. 2013. PMID: 23932902 Free PMC article.

10

Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines.

Ono M, Yamada K, Bensaddek D, Afzal V, Biddlestone J, Ortmann B, Mudie S, Boivin V, Scott MS, Rocha S, Lamond AI. Ono M, et al. PLoS One. 2016 Apr 29;11(4):e0154759. doi: 10.1371/journal.pone.0154759. eCollection 2016. PLoS One. 2016. PMID: 27128805 Free PMC article.

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