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Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity.
Milanski M, Degasperi G, Coope A, Morari J, Denis R, Cintra DE, Tsukumo DM, Anhe G, Amaral ME, Takahashi HK, Curi R, Oliveira HC, Carvalheira JB, Bordin S, Saad MJ, Velloso LA. Milanski M, et al. Among authors: morari j. J Neurosci. 2009 Jan 14;29(2):359-70. doi: 10.1523/JNEUROSCI.2760-08.2009. J Neurosci. 2009. PMID: 19144836 Free PMC article.
High-fat diet induces apoptosis of hypothalamic neurons.
Moraes JC, Coope A, Morari J, Cintra DE, Roman EA, Pauli JR, Romanatto T, Carvalheira JB, Oliveira AL, Saad MJ, Velloso LA. Moraes JC, et al. Among authors: morari j. PLoS One. 2009;4(4):e5045. doi: 10.1371/journal.pone.0005045. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340313 Free PMC article.
Grape peel powder promotes intestinal barrier homeostasis in acute TNBS-colitis: A major role for dietary fiber and fiber-bound polyphenols.
Maurer LH, Cazarin CBB, Quatrin A, Minuzzi NM, Costa EL, Morari J, Velloso LA, Leal RF, Rodrigues E, Bochi VC, Júnior MRM, Emanuelli T. Maurer LH, et al. Among authors: morari j. Food Res Int. 2019 Sep;123:425-439. doi: 10.1016/j.foodres.2019.04.068. Epub 2019 Apr 30. Food Res Int. 2019. PMID: 31284994 Free article.
Effects of Different Exercise Types on Chrna7 and Chrfam7a Expression in Healthy Normal Weight and Overweight Type 2 Diabetic Adults.
Mateus KCDS, Bonfante ILP, Sardeli AV, Duft RG, Gáspari AF, Trombeta JCDS, Morari J, Rodrigues B, Torsoni MA, Chacon-Mikahil MPT, Velloso LA, Cavaglieri CR. Mateus KCDS, et al. Among authors: morari j. Biomedicines. 2023 Feb 15;11(2):565. doi: 10.3390/biomedicines11020565. Biomedicines. 2023. PMID: 36831101 Free PMC article.
Flaxseed oil rich in omega-3 protects aorta against inflammation and endoplasmic reticulum stress partially mediated by GPR120 receptor in obese, diabetic and dyslipidemic mice models.
Moura-Assis A, Afonso MS, de Oliveira V, Morari J, Dos Santos GA, Koike M, Lottenberg AM, Ramos Catharino R, Velloso LA, Sanchez Ramos da Silva A, de Moura LP, Ropelle ER, Pauli JR, Cintra DEC. Moura-Assis A, et al. Among authors: morari j. J Nutr Biochem. 2018 Mar;53:9-19. doi: 10.1016/j.jnutbio.2017.09.015. Epub 2017 Oct 18. J Nutr Biochem. 2018. PMID: 29175142
IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition.
Ropelle ER, Flores MB, Cintra DE, Rocha GZ, Pauli JR, Morari J, de Souza CT, Moraes JC, Prada PO, Guadagnini D, Marin RM, Oliveira AG, Augusto TM, Carvalho HF, Velloso LA, Saad MJ, Carvalheira JB. Ropelle ER, et al. Among authors: morari j. PLoS Biol. 2010 Aug 24;8(8):e1000465. doi: 10.1371/journal.pbio.1000465. PLoS Biol. 2010. PMID: 20808781 Free PMC article. Retracted.
A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss.
Ropelle ER, Pauli JR, Fernandes MF, Rocco SA, Marin RM, Morari J, Souza KK, Dias MM, Gomes-Marcondes MC, Gontijo JA, Franchini KG, Velloso LA, Saad MJ, Carvalheira JB. Ropelle ER, et al. Among authors: morari j. Diabetes. 2008 Mar;57(3):594-605. doi: 10.2337/db07-0573. Epub 2007 Dec 5. Diabetes. 2008. PMID: 18057094 Retracted.
Combined training increases thermogenic fat activity in patients with overweight and type 2 diabetes.
Bonfante ILP, Monfort-Pires M, Duft RG, da Silva Mateus KC, de Lima Júnior JC, Dos Santos Trombeta JC, Finardi EAR, Brunelli DT, Morari J, de Lima JAB, Bellotto ML, de Araújo TMF, Ramos CD, Chacon-Mikahil MPT, Velloso LA, Cavaglieri CR. Bonfante ILP, et al. Among authors: morari j. Int J Obes (Lond). 2022 Jun;46(6):1145-1154. doi: 10.1038/s41366-022-01086-3. Epub 2022 Feb 16. Int J Obes (Lond). 2022. PMID: 35173278 Clinical Trial.
Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance.
Dragano NRV, Milbank E, Haddad-Tóvolli R, Garrido-Gil P, Nóvoa E, Fondevilla MF, Capelli V, Zanesco AM, Solon C, Morari J, Pires L, Estevez-Salguero Á, Beiroa D, González-García I, Barca-Mayo O, Diéguez C, Nogueiras R, Labandeira-García JL, Rexen Ulven E, Ulven T, Claret M, Velloso LA, López M. Dragano NRV, et al. Among authors: morari j. Mol Metab. 2024 Jan;79:101840. doi: 10.1016/j.molmet.2023.101840. Epub 2023 Nov 29. Mol Metab. 2024. PMID: 38036170 Free PMC article.
72 results