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Effect of Roxadustat on the Pharmacokinetics of Simvastatin, Rosuvastatin, and Atorvastatin in Healthy Subjects: Results From 3 Phase 1, Open-Label, 1-Sequence, Crossover Studies.
Groenendaal-van de Meent D, den Adel M, Kerbusch V, van Dijk J, Shibata T, Kato K, Schaddelee M. Groenendaal-van de Meent D, et al. Among authors: den adel m. Clin Pharmacol Drug Dev. 2022 Apr;11(4):486-501. doi: 10.1002/cpdd.1076. Epub 2022 Feb 19. Clin Pharmacol Drug Dev. 2022. PMID: 35182045 Free PMC article. Clinical Trial.
Effect of Multiple Doses of Omeprazole on the Pharmacokinetics, Safety, and Tolerability of Roxadustat in Healthy Subjects.
Groenendaal-van de Meent D, den Adel M, van Dijk J, Barroso-Fernandez B, El Galta R, Golor G, Schaddelee M. Groenendaal-van de Meent D, et al. Among authors: den adel m. Eur J Drug Metab Pharmacokinet. 2018 Dec;43(6):685-692. doi: 10.1007/s13318-018-0480-z. Eur J Drug Metab Pharmacokinet. 2018. PMID: 29752643 Free PMC article. Clinical Trial.
Effect of Kidney Function and Dialysis on the Pharmacokinetics and Pharmacodynamics of Roxadustat, an Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor.
Groenendaal-van de Meent D, Kerbusch V, Kaspera R, Barroso-Fernandez B, Galletti P, Klein GK, den Adel M. Groenendaal-van de Meent D, et al. Among authors: den adel m. Eur J Drug Metab Pharmacokinet. 2021 Jan;46(1):141-153. doi: 10.1007/s13318-020-00658-w. Eur J Drug Metab Pharmacokinet. 2021. PMID: 33165773 Free PMC article. Clinical Trial.
Effect of the Phosphate Binders Sevelamer Carbonate and Calcium Acetate on the Pharmacokinetics of Roxadustat After Concomitant or Time-separated Administration in Healthy Individuals.
Groenendaal-van de Meent D, Kerbusch V, Barroso-Fernandez B, den Adel M, van Dijk J, Golor G, Schaddelee M. Groenendaal-van de Meent D, et al. Among authors: den adel m. Clin Ther. 2021 Jun;43(6):1079-1091. doi: 10.1016/j.clinthera.2021.03.025. Epub 2021 May 5. Clin Ther. 2021. PMID: 33962762 Free article. Clinical Trial.
The Hypoxia-inducible Factor Prolyl-Hydroxylase Inhibitor Roxadustat (FG-4592) and Warfarin in Healthy Volunteers: A Pharmacokinetic and Pharmacodynamic Drug-Drug Interaction Study.
Groenendaal-van de Meent D, den Adel M, Rijnders S, Krebs-Brown A, Kerbusch V, Golor G, Schaddelee M. Groenendaal-van de Meent D, et al. Among authors: den adel m. Clin Ther. 2016 Apr;38(4):918-28. doi: 10.1016/j.clinthera.2016.02.010. Epub 2016 Mar 4. Clin Ther. 2016. PMID: 26947173 Clinical Trial.
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