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129 results

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miR-147b mediated suppression of DUSP8 promotes lung cancer progression.
Turkowski K, Herzberg F, Günther S, Weigert A, Haselbauer T, Fink L, Brunn D, Grimminger F, Seeger W, Sültmann H, Stiewe T, Pullamsetti SS, Savai R. Turkowski K, et al. Among authors: savai r. Oncogene. 2024 Apr;43(16):1178-1189. doi: 10.1038/s41388-024-02969-7. Epub 2024 Feb 23. Oncogene. 2024. PMID: 38396293 Free PMC article.
CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia.
Hirani DV, Thielen F, Mansouri S, Danopoulos S, Vohlen C, Haznedar-Karakaya P, Mohr J, Wilke R, Selle J, Grosch T, Mizik I, Odenthal M, Alvira CM, Kuiper-Makris C, Pryhuber GS, Pallasch C, van Koningsbruggen-Rietschel S, Al-Alam D, Seeger W, Savai R, Dötsch J, Alejandre Alcazar MA. Hirani DV, et al. Among authors: savai r. Inflamm Regen. 2023 Oct 24;43(1):52. doi: 10.1186/s41232-023-00301-6. Inflamm Regen. 2023. PMID: 37876024 Free PMC article.
Case Report: Durable therapy response to Osimertinib in rare EGFR Exon 18 mutated NSCLC.
Cekay M, Arndt PF, Dumitrascu R, Savai R, Braeuninger A, Gattenloehner S, Steiner D, Roller F, Tello K, Hattar K, Seeger W, Sibelius U, Grimminger F, Eul B. Cekay M, et al. Among authors: savai r. Front Oncol. 2023 Aug 16;13:1182391. doi: 10.3389/fonc.2023.1182391. eCollection 2023. Front Oncol. 2023. PMID: 37655099 Free PMC article.
Analysis of rare fusions in NSCLC: Genomic architecture and clinical implications.
Seker-Cin H, Tay TKY, Kazdal D, Kluck K, Ball M, Neumann O, Winter H, Herth F, Heußel CP, Savai R, Schirmacher P, Thomas M, Budczies J, Allgäuer M, Christopoulos P, Stenzinger A, Volckmar AL. Seker-Cin H, et al. Among authors: savai r. Lung Cancer. 2023 Oct;184:107317. doi: 10.1016/j.lungcan.2023.107317. Epub 2023 Jul 27. Lung Cancer. 2023. PMID: 37586177
ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth.
Karger A, Mansouri S, Leisegang MS, Weigert A, Günther S, Kuenne C, Wittig I, Zukunft S, Klatt S, Aliraj B, Klotz LV, Winter H, Mahavadi P, Fleming I, Ruppert C, Witte B, Alkoudmani I, Gattenlöhner S, Grimminger F, Seeger W, Pullamsetti SS, Savai R. Karger A, et al. Among authors: savai r. EMBO J. 2023 Sep 18;42(18):e111620. doi: 10.15252/embj.2022111620. Epub 2023 Aug 7. EMBO J. 2023. PMID: 37545364 Free PMC article.
The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization.
Zheng X, Sarode P, Weigert A, Turkowski K, Chelladurai P, Günther S, Kuenne C, Winter H, Stenzinger A, Reu S, Grimminger F, Stiewe T, Seeger W, Pullamsetti SS, Savai R. Zheng X, et al. Among authors: savai r. Cancer Res. 2023 Jul 14;83(14):2345-2357. doi: 10.1158/0008-5472.CAN-22-1270. Cancer Res. 2023. PMID: 37205635
Spatial profiling of the microenvironment reveals low intratumoral heterogeneity and STK11-associated immune evasion in therapy-naïve lung adenocarcinomas.
Goldschmid H, Kluck K, Ball M, Kirchner M, Allgäuer M, Winter H, Herth F, Heußel CP, Pullamsetti SS, Savai R, Yong TTK, Schirmacher P, Peters S, Thomas M, Christopoulos P, Budczies J, Stenzinger A, Kazdal D. Goldschmid H, et al. Among authors: savai r. Lung Cancer. 2023 Jun;180:107212. doi: 10.1016/j.lungcan.2023.107212. Epub 2023 Apr 23. Lung Cancer. 2023. PMID: 37141769
129 results