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Cannabidiol activates neuronal Kv7 channels.
Zhang HB, Heckman L, Niday Z, Jo S, Fujita A, Shim J, Pandey R, Al Jandal H, Jayakar S, Barrett LB, Smith J, Woolf CJ, Bean BP. Zhang HB, et al. Among authors: barrett lb. Elife. 2022 Feb 18;11:e73246. doi: 10.7554/eLife.73246. Elife. 2022. PMID: 35179483 Free PMC article.
Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons.
Cheng YC, Snavely A, Barrett LB, Zhang X, Herman C, Frost DJ, Riva P, Tochitsky I, Kawaguchi R, Singh B, Ivanis J, Huebner EA, Arvanites A, Oza V, Davidow L, Maeda R, Sakuma M, Grantham A, Wang Q, Chang AN, Pfaff K, Costigan M, Coppola G, Rubin LL, Schwer B, Alt FW, Woolf CJ. Cheng YC, et al. Among authors: barrett lb. Cell Rep. 2021 Sep 7;36(10):109666. doi: 10.1016/j.celrep.2021.109666. Cell Rep. 2021. PMID: 34496254 Free PMC article.
Diltiazem Promotes Regenerative Axon Growth.
Huebner EA, Budel S, Jiang Z, Omura T, Ho TS, Barrett L, Merkel JS, Pereira LM, Andrews NA, Wang X, Singh B, Kapur K, Costigan M, Strittmatter SM, Woolf CJ. Huebner EA, et al. Mol Neurobiol. 2019 Jun;56(6):3948-3957. doi: 10.1007/s12035-018-1349-5. Epub 2018 Sep 19. Mol Neurobiol. 2019. PMID: 30232777 Free PMC article.
Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer.
Cronin SJF, Rao S, Tejada MA, Turnes BL, Licht-Mayer S, Omura T, Brenneis C, Jacobs E, Barrett L, Latremoliere A, Andrews N, Channon KM, Latini A, Arvanites AC, Davidow LS, Costigan M, Rubin LL, Penninger JM, Woolf CJ. Cronin SJF, et al. Sci Transl Med. 2022 Aug 31;14(660):eabj1531. doi: 10.1126/scitranslmed.abj1531. Epub 2022 Aug 31. Sci Transl Med. 2022. PMID: 36044597 Free PMC article.
Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1.
Costigan M, Belfer I, Griffin RS, Dai F, Barrett LB, Coppola G, Wu T, Kiselycznyk C, Poddar M, Lu Y, Diatchenko L, Smith S, Cobos EJ, Zaykin D, Allchorne A, Gershon E, Livneh J, Shen PH, Nikolajsen L, Karppinen J, Männikkö M, Kelempisioti A, Goldman D, Maixner W, Geschwind DH, Max MB, Seltzer Z, Woolf CJ. Costigan M, et al. Among authors: barrett lb. Brain. 2010 Sep;133(9):2519-27. doi: 10.1093/brain/awq195. Epub 2010 Aug 18. Brain. 2010. PMID: 20724292 Free PMC article.
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.
Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ. Wainger BJ, et al. Nat Neurosci. 2015 Jan;18(1):17-24. doi: 10.1038/nn.3886. Epub 2014 Nov 24. Nat Neurosci. 2015. PMID: 25420066 Free PMC article.
A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program.
Chandran V, Coppola G, Nawabi H, Omura T, Versano R, Huebner EA, Zhang A, Costigan M, Yekkirala A, Barrett L, Blesch A, Michaelevski I, Davis-Turak J, Gao F, Langfelder P, Horvath S, He Z, Benowitz L, Fainzilber M, Tuszynski M, Woolf CJ, Geschwind DH. Chandran V, et al. Neuron. 2016 Mar 2;89(5):956-70. doi: 10.1016/j.neuron.2016.01.034. Epub 2016 Feb 18. Neuron. 2016. PMID: 26898779 Free PMC article.
Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
Latremoliere A, Latini A, Andrews N, Cronin SJ, Fujita M, Gorska K, Hovius R, Romero C, Chuaiphichai S, Painter M, Miracca G, Babaniyi O, Remor AP, Duong K, Riva P, Barrett LB, Ferreirós N, Naylor A, Penninger JM, Tegeder I, Zhong J, Blagg J, Channon KM, Johnsson K, Costigan M, Woolf CJ. Latremoliere A, et al. Among authors: barrett lb. Neuron. 2015 Jun 17;86(6):1393-406. doi: 10.1016/j.neuron.2015.05.033. Neuron. 2015. PMID: 26087165 Free PMC article.
44 results