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Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability.
Ghosh JC, Perego M, Agarwal E, Bertolini I, Wang Y, Goldman AR, Tang HY, Kossenkov AV, Landis CJ, Languino LR, Plow EF, Morotti A, Ottobrini L, Locatelli M, Speicher DW, Caino MC, Cassel J, Salvino JM, Robert ME, Vaira V, Altieri DC. Ghosh JC, et al. Among authors: vaira v. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2115624119. doi: 10.1073/pnas.2115624119. Proc Natl Acad Sci U S A. 2022. PMID: 35177476 Free PMC article.
Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s.
Chae YC, Caino MC, Lisanti S, Ghosh JC, Dohi T, Danial NN, Villanueva J, Ferrero S, Vaira V, Santambrogio L, Bosari S, Languino LR, Herlyn M, Altieri DC. Chae YC, et al. Among authors: vaira v. Cancer Cell. 2012 Sep 11;22(3):331-44. doi: 10.1016/j.ccr.2012.07.015. Cancer Cell. 2012. PMID: 22975376 Free PMC article.
Regulation of lung cancer metastasis by Klf4-Numb-like signaling.
Vaira V, Faversani A, Martin NM, Garlick DS, Ferrero S, Nosotti M, Kissil JL, Bosari S, Altieri DC. Vaira V, et al. Cancer Res. 2013 Apr 15;73(8):2695-705. doi: 10.1158/0008-5472.CAN-12-4232. Epub 2013 Feb 25. Cancer Res. 2013. PMID: 23440423 Free PMC article.
Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells.
Caino MC, Chae YC, Vaira V, Ferrero S, Nosotti M, Martin NM, Weeraratna A, O'Connell M, Jernigan D, Fatatis A, Languino LR, Bosari S, Altieri DC. Caino MC, et al. Among authors: vaira v. J Clin Invest. 2013 Jul;123(7):2907-20. doi: 10.1172/JCI67841. Epub 2013 Jun 10. J Clin Invest. 2013. PMID: 23921130 Free PMC article.
Adaptive mitochondrial reprogramming and resistance to PI3K therapy.
Ghosh JC, Siegelin MD, Vaira V, Faversani A, Tavecchio M, Chae YC, Lisanti S, Rampini P, Giroda M, Caino MC, Seo JH, Kossenkov AV, Michalek RD, Schultz DC, Bosari S, Languino LR, Altieri DC. Ghosh JC, et al. Among authors: vaira v. J Natl Cancer Inst. 2015 Feb 3;107(3):dju502. doi: 10.1093/jnci/dju502. Print 2015 Mar. J Natl Cancer Inst. 2015. PMID: 25650317 Free PMC article.
114 results