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Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability.
Ghosh JC, Perego M, Agarwal E, Bertolini I, Wang Y, Goldman AR, Tang HY, Kossenkov AV, Landis CJ, Languino LR, Plow EF, Morotti A, Ottobrini L, Locatelli M, Speicher DW, Caino MC, Cassel J, Salvino JM, Robert ME, Vaira V, Altieri DC. Ghosh JC, et al. Among authors: locatelli m. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2115624119. doi: 10.1073/pnas.2115624119. Proc Natl Acad Sci U S A. 2022. PMID: 35177476 Free PMC article.
The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma.
Di Cristofori A, Ferrero S, Bertolini I, Gaudioso G, Russo MV, Berno V, Vanini M, Locatelli M, Zavanone M, Rampini P, Vaccari T, Caroli M, Vaira V. Di Cristofori A, et al. Among authors: locatelli m. Oncotarget. 2015 Jul 10;6(19):17514-31. doi: 10.18632/oncotarget.4239. Oncotarget. 2015. PMID: 26020805 Free PMC article.
Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming.
Chae YC, Vaira V, Caino MC, Tang HY, Seo JH, Kossenkov AV, Ottobrini L, Martelli C, Lucignani G, Bertolini I, Locatelli M, Bryant KG, Ghosh JC, Lisanti S, Ku B, Bosari S, Languino LR, Speicher DW, Altieri DC. Chae YC, et al. Among authors: locatelli m. Cancer Cell. 2016 Aug 8;30(2):257-272. doi: 10.1016/j.ccell.2016.07.004. Cancer Cell. 2016. PMID: 27505672 Free PMC article.
Mitochondrial fitness and cancer risk.
Kossenkov AV, Milcarek A, Notta F, Jang GH, Wilson JM, Gallinger S, Zhou DC, Ding L, Ghosh JC, Perego M, Morotti A, Locatelli M, Robert ME, Vaira V, Altieri DC. Kossenkov AV, et al. Among authors: locatelli m. PLoS One. 2022 Oct 12;17(10):e0273520. doi: 10.1371/journal.pone.0273520. eCollection 2022. PLoS One. 2022. PMID: 36223343 Free PMC article.
750 results