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Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood.
Decaris ML, Li KW, Emson CL, Gatmaitan M, Liu S, Wang Y, Nyangau E, Colangelo M, Angel TE, Beysen C, Cui J, Hernandez C, Lazaro L, Brenner DA, Turner SM, Hellerstein MK, Loomba R. Decaris ML, et al. Among authors: hellerstein mk. Hepatology. 2017 Jan;65(1):78-88. doi: 10.1002/hep.28860. Epub 2016 Nov 15. Hepatology. 2017. PMID: 27706836 Free PMC article.
Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis.
Lawitz EJ, Coste A, Poordad F, Alkhouri N, Loo N, McColgan BJ, Tarrant JM, Nguyen T, Han L, Chung C, Ray AS, McHutchison JG, Subramanian GM, Myers RP, Middleton MS, Sirlin C, Loomba R, Nyangau E, Fitch M, Li K, Hellerstein M. Lawitz EJ, et al. Clin Gastroenterol Hepatol. 2018 Dec;16(12):1983-1991.e3. doi: 10.1016/j.cgh.2018.04.042. Epub 2018 Apr 26. Clin Gastroenterol Hepatol. 2018. PMID: 29705265
Discovery of Half-life of Circulating Hepatitis B Surface Antigen in Patients With Chronic Hepatitis B Infection Using Heavy Water Labeling.
Loomba R, Decaris M, Li KW, Shankaran M, Mohammed H, Matthews M, Richards LM, Nguyen P, Rizo E, Andrews B, Soto R, Angel T, Suri V, Kitrinos KM, Barnes D, Czerwieniec G, Brendza K, Subramanian GM, Gaggar A, Hellerstein MK. Loomba R, et al. Among authors: hellerstein mk. Clin Infect Dis. 2019 Jul 18;69(3):542-545. doi: 10.1093/cid/ciy1100. Clin Infect Dis. 2019. PMID: 30590481
Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease.
Smith GI, Shankaran M, Yoshino M, Schweitzer GG, Chondronikola M, Beals JW, Okunade AL, Patterson BW, Nyangau E, Field T, Sirlin CB, Talukdar S, Hellerstein MK, Klein S. Smith GI, et al. Among authors: hellerstein mk. J Clin Invest. 2020 Mar 2;130(3):1453-1460. doi: 10.1172/JCI134165. J Clin Invest. 2020. PMID: 31805015 Free PMC article. Clinical Trial.
298 results