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Optimized M24B Aminopeptidase Inhibitors for CARD8 Inflammasome Activation.
J Med Chem. 2023 Feb 23;66(4):2589-2607. doi: 10.1021/acs.jmedchem.2c01535. Epub 2023 Feb 1.
J Med Chem. 2023.
PMID: 36724486
Free PMC article.
M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome.
Rao SD, Chen Q, Wang Q, Orth-He EL, Saoi M, Griswold AR, Bhattacharjee A, Ball DP, Huang HC, Chui AJ, Covelli DJ, You S, Cross JR, Bachovchin DA.
Rao SD, et al. Among authors: covelli dj.
Nat Chem Biol. 2022 May;18(5):565-574. doi: 10.1038/s41589-021-00964-7. Epub 2022 Feb 14.
Nat Chem Biol. 2022.
PMID: 35165443
Free PMC article.
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