LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria.
Yang Q, Liu P, Anderson NS, Shpilka T, Du Y, Naresh NU, Li R, Zhu LJ, Luk K, Lavelle J, Zeinert RD, Chien P, Wolfe SA, Haynes CM.
Yang Q, et al. Among authors: shpilka t.
Nat Cell Biol. 2022 Feb;24(2):181-193. doi: 10.1038/s41556-021-00840-5. Epub 2022 Feb 14.
Nat Cell Biol. 2022.
PMID: 35165413
Free PMC article.