DPP-4 Inhibitor Sitagliptin Improves Cardiac Function and Glucose Homeostasis and Ameliorates β-Cell Dysfunction Together with Reducing S6K1 Activation and IRS-1 and IRS-2 Degradation in Obesity Female Mice.
Qiao S, Mao G, Li H, Ma Z, Hong L, Zhang H, Wang C, An J.
Qiao S, et al. Among authors: an j.
J Diabetes Res. 2018 Jul 17;2018:3641516. doi: 10.1155/2018/3641516. eCollection 2018.
J Diabetes Res. 2018.
PMID: 30116740
Free PMC article.
In this study, we explored whether DPP-4 inhibitor sitagliptin (SIT) is involved in the protection of cardiac function and beta-cell function using an obesity female mouse model. METHODS: Six-week-old C57BL6/J mice were fed a high fat and fructose Western diet with …
In this study, we explored whether DPP-4 inhibitor sitagliptin (SIT) is involved in the protection of cardiac function and beta-cell functio …