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Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss.
Marchione DM, Lisby A, Viaene AN, Santi M, Nasrallah M, Wang LP, Williams EA, Larque AB, Chebib I, Garcia BA, Wojcik JB. Marchione DM, et al. Among authors: lisby a. Mod Pathol. 2019 Oct;32(10):1434-1446. doi: 10.1038/s41379-019-0287-8. Epub 2019 Jun 7. Mod Pathol. 2019. PMID: 31175328 Free PMC article.