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CCN2 (Cellular Communication Network Factor 2) Deletion Alters Vascular Integrity and Function Predisposing to Aneurysm Formation.
Rodrigues-Díez RR, Tejera-Muñoz A, Esteban V, Steffensen LB, Rodrigues-Díez R, Orejudo M, Rayego-Mateos S, Falke LL, Cannata-Ortiz P, Ortiz A, Egido J, Mallat Z, Briones AM, Bajo MA, Goldschmeding R, Ruiz-Ortega M. Rodrigues-Díez RR, et al. Among authors: goldschmeding r. Hypertension. 2022 Mar;79(3):e42-e55. doi: 10.1161/HYPERTENSIONAHA.121.18201. Epub 2021 Dec 30. Hypertension. 2022. PMID: 35138869
A perspective on anti-CCN2 therapy for chronic kidney disease.
Falke LL, Goldschmeding R, Nguyen TQ. Falke LL, et al. Among authors: goldschmeding r. Nephrol Dial Transplant. 2014 Feb;29 Suppl 1:i30-i37. doi: 10.1093/ndt/gft430. Nephrol Dial Transplant. 2014. PMID: 24493868 Review.
Loss of expression of protein phosphatase magnesium-dependent 1A during kidney injury promotes fibrotic maladaptive repair.
Samarakoon R, Rehfuss A, Khakoo NS, Falke LL, Dobberfuhl AD, Helo S, Overstreet JM, Goldschmeding R, Higgins PJ. Samarakoon R, et al. Among authors: goldschmeding r. FASEB J. 2016 Oct;30(10):3308-3320. doi: 10.1096/fj.201500105R. Epub 2016 Jun 21. FASEB J. 2016. PMID: 27328942 Free PMC article.
These findings establish PPM1A as a novel repressor of the SMAD3 pathway in renal fibrosis and as a new therapeutic target in patients with chronic kidney disease.-Samarakoon, R., Rehfuss, A., Khakoo, N. S., Falke, L. L., Dobberfuhl, A. D., Helo, S., Overstreet, J. M., …
These findings establish PPM1A as a novel repressor of the SMAD3 pathway in renal fibrosis and as a new therapeutic target in patients with …
266 results