Tsai YM - Search Results

1

A siRNA targets and inhibits a broad range of SARS-CoV-2 infections including Delta variant.

Chang YC, Yang CF, Chen YF, Yang CC, Chou YL, Chou HW, Chang TY, Chao TL, Hsu SC, Ieong SM, Tsai YM, Liu PC, Chin YF, Fang JT, Kao HC, Lu HY, Chang JY, Weng RS, Tu QW, Chang FY, Huang KY, Lee TY, Chang SY, Yang PC. Chang YC, et al. Among authors: tsai ym. EMBO Mol Med. 2022 Apr 7;14(4):e15298. doi: 10.15252/emmm.202115298. Epub 2022 Feb 21. EMBO Mol Med. 2022. PMID: 35138028 Free PMC article.

2

The application of intramolecular radical cyclizations of acylsilanes in the regiospecific formation of cyclic silyl enol ethers.

Huang CH, Chang SY, Wang NS, Tsai YM. Huang CH, et al. Among authors: tsai ym. J Org Chem. 2001 Dec 28;66(26):8983-91. doi: 10.1021/jo010883s. J Org Chem. 2001. PMID: 11749631

3

Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects.

Cheng YW, Chao TL, Li CL, Chiu MF, Kao HC, Wang SH, Pang YH, Lin CH, Tsai YM, Lee WH, Tao MH, Ho TC, Wu PY, Jang LT, Chen PJ, Chang SY, Yeh SH. Cheng YW, et al. Among authors: tsai ym. Cell Rep. 2020 Oct 13;33(2):108254. doi: 10.1016/j.celrep.2020.108254. Epub 2020 Sep 23. Cell Rep. 2020. PMID: 33007239 Free PMC article.

4

Kinetic Characterization and Inhibitor Screening for the Proteases Leading to Identification of Drugs against SARS-CoV-2.

Kuo CJ, Chao TL, Kao HC, Tsai YM, Liu YK, Wang LH, Hsieh MC, Chang SY, Liang PH. Kuo CJ, et al. Among authors: tsai ym. Antimicrob Agents Chemother. 2021 Mar 18;65(4):e02577-20. doi: 10.1128/AAC.02577-20. Print 2021 Mar 18. Antimicrob Agents Chemother. 2021. PMID: 33526482 Free PMC article.

5

D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Virus Titer via Enhanced Furin-Mediated Spike Cleavage.

Cheng YW, Chao TL, Li CL, Wang SH, Kao HC, Tsai YM, Wang HY, Hsieh CL, Lin YY, Chen PJ, Chang SY, Yeh SH. Cheng YW, et al. Among authors: tsai ym. mBio. 2021 Aug 31;12(4):e0058721. doi: 10.1128/mBio.00587-21. Epub 2021 Jul 27. mBio. 2021. PMID: 34311586 Free PMC article.

6

Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models.

Huang HY, Liao HY, Chen X, Wang SW, Cheng CW, Shahed-Al-Mahmud M, Liu YM, Mohapatra A, Chen TH, Lo JM, Wu YM, Ma HH, Chang YH, Tsai HY, Chou YC, Hsueh YP, Tsai CY, Huang PY, Chang SY, Chao TL, Kao HC, Tsai YM, Chen YH, Wu CY, Jan JT, Cheng TR, Lin KI, Ma C, Wong CH. Huang HY, et al. Among authors: tsai cy, tsai ym, tsai hy. Sci Transl Med. 2022 Apr 6;14(639):eabm0899. doi: 10.1126/scitranslmed.abm0899. Epub 2022 Apr 6. Sci Transl Med. 2022. PMID: 35230146 Free PMC article.

7

Neutralizing Monoclonal Antibodies Inhibit SARS-CoV-2 Infection through Blocking Membrane Fusion.

Li CJ, Chao TL, Chang TY, Hsiao CC, Lu DC, Chiang YW, Lai GC, Tsai YM, Fang JT, Ieong S, Wang JT, Chang SY, Chang SC. Li CJ, et al. Among authors: tsai ym. Microbiol Spectr. 2022 Apr 27;10(2):e0181421. doi: 10.1128/spectrum.01814-21. Epub 2022 Mar 16. Microbiol Spectr. 2022. PMID: 35293796 Free PMC article.

8

Neutralization or enhancement of SARS-CoV-2 infection by a monoclonal antibody targeting a specific epitope in the spike receptor-binding domain.

Lai GC, Chao TL, Lin SY, Kao HC, Tsai YM, Lu DC, Chiang YW, Chang SY, Chang SC. Lai GC, et al. Among authors: tsai ym. Antiviral Res. 2022 Apr;200:105290. doi: 10.1016/j.antiviral.2022.105290. Epub 2022 Mar 13. Antiviral Res. 2022. PMID: 35296418 Free PMC article.

9

Disulfiram blocked cell entry of SARS-CoV-2 via inhibiting the interaction of spike protein and ACE2.

Chen HF, Hsueh PR, Liu YY, Chen Y, Chang SY, Wang WJ, Wu CS, Tsai YM, Liu YS, Su WC, Chou YC, Hung MC. Chen HF, et al. Among authors: tsai ym. Am J Cancer Res. 2022 Jul 15;12(7):3333-3346. eCollection 2022. Am J Cancer Res. 2022. PMID: 35968340 Free PMC article.

10

Tag-Free SARS-CoV-2 Receptor Binding Domain (RBD), but Not C-Terminal Tagged SARS-CoV-2 RBD, Induces a Rapid and Potent Neutralizing Antibody Response.

Lin TW, Huang PH, Liao BH, Chao TL, Tsai YM, Chang SC, Chang SY, Chen HW. Lin TW, et al. Among authors: tsai ym. Vaccines (Basel). 2022 Oct 30;10(11):1839. doi: 10.3390/vaccines10111839. Vaccines (Basel). 2022. PMID: 36366348 Free PMC article.

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