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Page 1
Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation.
Failer T, Amponsah-Offeh M, Neuwirth A, Kourtzelis I, Subramanian P, Mirtschink P, Peitzsch M, Matschke K, Tugtekin SM, Kajikawa T, Li X, Steglich A, Gembardt F, Wegner AC, Hugo C, Hajishengallis G, Chavakis T, Deussen A, Todorov V, Kopaliani I. Failer T, et al. Among authors: neuwirth a. J Clin Invest. 2022 Mar 15;132(6):e126155. doi: 10.1172/JCI126155. J Clin Invest. 2022. PMID: 35133978 Free PMC article.
Developmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination.
Choi EY, Lim JH, Neuwirth A, Economopoulou M, Chatzigeorgiou A, Chung KJ, Bittner S, Lee SH, Langer H, Samus M, Kim H, Cho GS, Ziemssen T, Bdeir K, Chavakis E, Koh JY, Boon L, Hosur K, Bornstein SR, Meuth SG, Hajishengallis G, Chavakis T. Choi EY, et al. Among authors: neuwirth a. Mol Psychiatry. 2015 Jul;20(7):880-888. doi: 10.1038/mp.2014.146. Epub 2014 Nov 11. Mol Psychiatry. 2015. PMID: 25385367 Free PMC article.
DHEA Inhibits Leukocyte Recruitment through Regulation of the Integrin Antagonist DEL-1.
Ziogas A, Maekawa T, Wiessner JR, Le TT, Sprott D, Troullinaki M, Neuwirth A, Anastasopoulou V, Grossklaus S, Chung KJ, Sperandio M, Chavakis T, Hajishengallis G, Alexaki VI. Ziogas A, et al. Among authors: neuwirth a. J Immunol. 2020 Mar 1;204(5):1214-1224. doi: 10.4049/jimmunol.1900746. Epub 2020 Jan 24. J Immunol. 2020. PMID: 31980574 Free PMC article.
Endogenous developmental endothelial locus-1 limits ischaemia-related angiogenesis by blocking inflammation.
Klotzsche-von Ameln A, Cremer S, Hoffmann J, Schuster P, Khedr S, Korovina I, Troullinaki M, Neuwirth A, Sprott D, Chatzigeorgiou A, Economopoulou M, Orlandi A, Hain A, Zeiher AM, Deussen A, Hajishengallis G, Dimmeler S, Chavakis T, Chavakis E. Klotzsche-von Ameln A, et al. Among authors: neuwirth a. Thromb Haemost. 2017 Jun 2;117(6):1150-1163. doi: 10.1160/TH16-05-0354. Epub 2017 Apr 27. Thromb Haemost. 2017. PMID: 28447099 Free PMC article.
Erratum to: Endogenous developmental endothelial locus-1 limits ischaemia-related angiogenesis by blocking inflammation.
Klotzsche-von Ameln A, Cremer S, Hoffmann J, Schuster P, Khedr S, Korovina I, Troullinaki M, Neuwirth A, Sprott D, Chatzigeorgiou A, Economopoulou M, Orlandi A, Hain A, Zeiher AM, Deussen A, Hajishengallis G, Dimmeler S, Chavakis T, Chavakis E. Klotzsche-von Ameln A, et al. Among authors: neuwirth a. Thromb Haemost. 2017 Jun;117(6):e1. doi: 10.1055/s-0039-1696711. Epub 2019 Dec 16. Thromb Haemost. 2017. PMID: 31842234 No abstract available.
Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.
Kalafati L, Kourtzelis I, Schulte-Schrepping J, Li X, Hatzioannou A, Grinenko T, Hagag E, Sinha A, Has C, Dietz S, de Jesus Domingues AM, Nati M, Sormendi S, Neuwirth A, Chatzigeorgiou A, Ziogas A, Lesche M, Dahl A, Henry I, Subramanian P, Wielockx B, Murray P, Mirtschink P, Chung KJ, Schultze JL, Netea MG, Hajishengallis G, Verginis P, Mitroulis I, Chavakis T. Kalafati L, et al. Among authors: neuwirth a. Cell. 2020 Oct 29;183(3):771-785.e12. doi: 10.1016/j.cell.2020.09.058. Cell. 2020. PMID: 33125892 Free PMC article.
Hematopoietic hypoxia-inducible factor 2α deficiency ameliorates pathological retinal neovascularization via modulation of endothelial cell apoptosis.
Korovina I, Neuwirth A, Sprott D, Weber S, Sardar Pasha SPB, Gercken B, Breier G, El-Armouche A, Deussen A, Karl MO, Wielockx B, Chavakis T, Klotzsche-von Ameln A. Korovina I, et al. Among authors: neuwirth a. FASEB J. 2019 Feb;33(2):1758-1770. doi: 10.1096/fj.201800430R. Epub 2018 Aug 29. FASEB J. 2019. PMID: 30156910
A hallmark of proliferative retinopathies, such as retinopathy of prematurity (ROP), is a pathological neovascularization orchestrated by hypoxia and the resulting hypoxia-inducible factor (HIF)-dependent response. ...Our findings not only provide novel insights reg
A hallmark of proliferative retinopathies, such as retinopathy of prematurity (ROP), is a pathological neovascularization orch
HIF1α is a direct regulator of steroidogenesis in the adrenal gland.
Watts D, Stein J, Meneses A, Bechmann N, Neuwirth A, Kaden D, Krüger A, Sinha A, Alexaki VI, Luis Gustavo Perez-Rivas, Kircher S, Martinez A, Theodoropoulou M, Eisenhofer G, Peitzsch M, El-Armouche A, Chavakis T, Wielockx B. Watts D, et al. Among authors: neuwirth a. Cell Mol Life Sci. 2021 Apr;78(7):3577-3590. doi: 10.1007/s00018-020-03750-1. Epub 2021 Jan 19. Cell Mol Life Sci. 2021. PMID: 33464382 Free PMC article.
DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway.
Alexaki VI, Fodelianaki G, Neuwirth A, Mund C, Kourgiantaki A, Ieronimaki E, Lyroni K, Troullinaki M, Fujii C, Kanczkowski W, Ziogas A, Peitzsch M, Grossklaus S, Sönnichsen B, Gravanis A, Bornstein SR, Charalampopoulos I, Tsatsanis C, Chavakis T. Alexaki VI, et al. Among authors: neuwirth a. Mol Psychiatry. 2018 Jun;23(6):1410-1420. doi: 10.1038/mp.2017.167. Epub 2017 Sep 12. Mol Psychiatry. 2018. PMID: 28894299
102 results