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Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation.
Failer T, Amponsah-Offeh M, Neuwirth A, Kourtzelis I, Subramanian P, Mirtschink P, Peitzsch M, Matschke K, Tugtekin SM, Kajikawa T, Li X, Steglich A, Gembardt F, Wegner AC, Hugo C, Hajishengallis G, Chavakis T, Deussen A, Todorov V, Kopaliani I. Failer T, et al. Among authors: kourtzelis i. J Clin Invest. 2022 Mar 15;132(6):e126155. doi: 10.1172/JCI126155. J Clin Invest. 2022. PMID: 35133978 Free PMC article.
Stromal cell-derived DEL-1 inhibits Tfh cell activation and inflammatory arthritis.
Wang H, Li X, Kajikawa T, Shin J, Lim JH, Kourtzelis I, Nagai K, Korostoff JM, Grossklaus S, Naumann R, Chavakis T, Hajishengallis G. Wang H, et al. Among authors: kourtzelis i. J Clin Invest. 2021 Oct 1;131(19):e150578. doi: 10.1172/JCI150578. J Clin Invest. 2021. PMID: 34403362 Free PMC article.
Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche.
Mitroulis I, Chen LS, Singh RP, Kourtzelis I, Economopoulou M, Kajikawa T, Troullinaki M, Ziogas A, Ruppova K, Hosur K, Maekawa T, Wang B, Subramanian P, Tonn T, Verginis P, von Bonin M, Wobus M, Bornhäuser M, Grinenko T, Di Scala M, Hidalgo A, Wielockx B, Hajishengallis G, Chavakis T. Mitroulis I, et al. Among authors: kourtzelis i. J Clin Invest. 2017 Oct 2;127(10):3624-3639. doi: 10.1172/JCI92571. Epub 2017 Aug 28. J Clin Invest. 2017. PMID: 28846069 Free PMC article.
DEL-1 promotes macrophage efferocytosis and clearance of inflammation.
Kourtzelis I, Li X, Mitroulis I, Grosser D, Kajikawa T, Wang B, Grzybek M, von Renesse J, Czogalla A, Troullinaki M, Ferreira A, Doreth C, Ruppova K, Chen LS, Hosur K, Lim JH, Chung KJ, Grossklaus S, Tausche AK, Joosten LAB, Moutsopoulos NM, Wielockx B, Castrillo A, Korostoff JM, Coskun Ü, Hajishengallis G, Chavakis T. Kourtzelis I, et al. Nat Immunol. 2019 Jan;20(1):40-49. doi: 10.1038/s41590-018-0249-1. Epub 2018 Nov 19. Nat Immunol. 2019. PMID: 30455459 Free PMC article.
Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation.
Kourtzelis I, Kotlabova K, Lim JH, Mitroulis I, Ferreira A, Chen LS, Gercken B, Steffen A, Kemter E, Klotzsche-von Ameln A, Waskow C, Hosur K, Chatzigeorgiou A, Ludwig B, Wolf E, Hajishengallis G, Chavakis T. Kourtzelis I, et al. Thromb Haemost. 2016 Apr;115(4):781-8. doi: 10.1160/TH15-05-0429. Epub 2015 Dec 17. Thromb Haemost. 2016. PMID: 26676803 Free PMC article.
Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.
Kalafati L, Kourtzelis I, Schulte-Schrepping J, Li X, Hatzioannou A, Grinenko T, Hagag E, Sinha A, Has C, Dietz S, de Jesus Domingues AM, Nati M, Sormendi S, Neuwirth A, Chatzigeorgiou A, Ziogas A, Lesche M, Dahl A, Henry I, Subramanian P, Wielockx B, Murray P, Mirtschink P, Chung KJ, Schultze JL, Netea MG, Hajishengallis G, Verginis P, Mitroulis I, Chavakis T. Kalafati L, et al. Among authors: kourtzelis i. Cell. 2020 Oct 29;183(3):771-785.e12. doi: 10.1016/j.cell.2020.09.058. Cell. 2020. PMID: 33125892 Free PMC article.
43 results