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NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation.
Sharrock AV, Mulligan TS, Hall KR, Williams EM, White DT, Zhang L, Emmerich K, Matthews F, Nimmagadda S, Washington S, Le KD, Meir-Levi D, Cox OL, Saxena MT, Calof AL, Lopez-Burks ME, Lander AD, Ding D, Ji H, Ackerley DF, Mumm JS. Sharrock AV, et al. Among authors: hall kr. Nat Methods. 2022 Feb;19(2):205-215. doi: 10.1038/s41592-021-01364-4. Epub 2022 Feb 7. Nat Methods. 2022. PMID: 35132245 Free PMC article.
Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa.
Zhang L, Chen C, Fu J, Lilley B, Berlinicke C, Hansen B, Ding D, Wang G, Wang T, Shou D, Ye Y, Mulligan T, Emmerich K, Saxena MT, Hall KR, Sharrock AV, Brandon C, Park H, Kam TI, Dawson VL, Dawson TM, Shim JS, Hanes J, Ji H, Liu JO, Qian J, Ackerley DF, Rohrer B, Zack DJ, Mumm JS. Zhang L, et al. Among authors: hall kr. Elife. 2021 Jun 29;10:e57245. doi: 10.7554/eLife.57245. Elife. 2021. PMID: 34184634 Free PMC article.
Total Synthesis and Bioactivity Studies of Fungal Metabolite (-)-TAN-2483B.
McCone JAJ, Somarathne KK, Orme CL, Hewitt RJ, Grant ER, Hall KR, Ackerley DF, La Flamme AC, Harvey JE. McCone JAJ, et al. Among authors: hall kr. Org Lett. 2020 Dec 18;22(24):9427-9432. doi: 10.1021/acs.orglett.0c03303. Epub 2020 Nov 24. Org Lett. 2020. PMID: 33232161
Mutational dissection of a hole hopping route in a lytic polysaccharide monooxygenase (LPMO).
Ayuso-Fernández I, Emrich-Mills TZ, Haak J, Golten O, Hall KR, Schwaiger L, Moe TS, Stepnov AA, Ludwig R, Cutsail Iii GE, Sørlie M, Kjendseth Røhr Å, Eijsink VGH. Ayuso-Fernández I, et al. Among authors: hall kr. Nat Commun. 2024 May 10;15(1):3975. doi: 10.1038/s41467-024-48245-w. Nat Commun. 2024. PMID: 38729930 Free PMC article.
46 results