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Specific PFKFB3 Inhibitor Memorably Ameliorates Intervertebral Disc Degeneration via Inhibiting NF-κB and MAPK Signaling Pathway and Reprogramming of Energy Metabolism of Nucleus Pulposus Cells.
Cao X, Wang X, Rong K, Liu K, Yang X, Zhou T, Zhang P, Guo J, Ma H, Qin A, Zhao J. Cao X, et al. Among authors: wang x. Oxid Med Cell Longev. 2022 Sep 21;2022:7548145. doi: 10.1155/2022/7548145. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 36187335 Free PMC article.
Verapamil attenuates intervertebral disc degeneration by suppressing ROS overproduction and pyroptosis via targeting the Nrf2/TXNIP/NLRP3 axis in four-week puncture-induced rat models both in vivo and in vitro.
Chen Y, Cao X, Pan B, Du H, Li B, Yang X, Chen X, Wang X, Zhou T, Qin A, Zhao C, Zhao J. Chen Y, et al. Among authors: wang x. Int Immunopharmacol. 2023 Oct;123:110789. doi: 10.1016/j.intimp.2023.110789. Epub 2023 Aug 12. Int Immunopharmacol. 2023. PMID: 37579541 Free article.
Loss of DDRGK1 impairs IRE1α UFMylation in spondyloepiphyseal dysplasia.
Yang X, Zhou T, Wang X, Xia Y, Cao X, Cheng X, Cao Y, Ma P, Ma H, Qin A, Zhao J. Yang X, et al. Among authors: wang x. Int J Biol Sci. 2023 Sep 4;19(15):4709-4725. doi: 10.7150/ijbs.82765. eCollection 2023. Int J Biol Sci. 2023. PMID: 37781516 Free PMC article.
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