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RNA-DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells.
Ke W, Hong E, Saito RF, Rangel MC, Wang J, Viard M, Richardson M, Khisamutdinov EF, Panigaj M, Dokholyan NV, Chammas R, Dobrovolskaia MA, Afonin KA. Ke W, et al. Among authors: dokholyan nv. Nucleic Acids Res. 2019 Feb 20;47(3):1350-1361. doi: 10.1093/nar/gky1215. Nucleic Acids Res. 2019. PMID: 30517685 Free PMC article.
RNA Fibers as Optimized Nanoscaffolds for siRNA Coordination and Reduced Immunological Recognition.
Rackley L, Stewart JM, Salotti J, Krokhotin A, Shah A, Halman JR, Juneja R, Smollett J, Lee L, Roark K, Viard M, Tarannum M, Vivero-Escoto J, Johnson PF, Dobrovolskaia MA, Dokholyan NV, Franco E, Afonin KA. Rackley L, et al. Among authors: dokholyan nv. Adv Funct Mater. 2018 Nov 28;28(48):1805959. doi: 10.1002/adfm.201805959. Epub 2018 Oct 9. Adv Funct Mater. 2018. PMID: 31258458 Free PMC article.
Mapping allosteric communications within individual proteins.
Wang J, Jain A, McDonald LR, Gambogi C, Lee AL, Dokholyan NV. Wang J, et al. Among authors: dokholyan nv. Nat Commun. 2020 Jul 31;11(1):3862. doi: 10.1038/s41467-020-17618-2. Nat Commun. 2020. PMID: 32737291 Free PMC article.
329 results