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Why Single-Cell Sequencing Has Promise in MDS.
Zhang X, Grimes HL. Zhang X, et al. Among authors: grimes hl. Front Oncol. 2021 Dec 2;11:769753. doi: 10.3389/fonc.2021.769753. eCollection 2021. Front Oncol. 2021. PMID: 34926276 Free PMC article. Review.
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors.
Zhang X, Song B, Carlino MJ, Li G, Ferchen K, Chen M, Thompson EN, Kain BN, Schnell D, Thakkar K, Kouril M, Jin K, Hay SB, Sen S, Bernardicius D, Ma S, Bennett SN, Croteau J, Salvatori O, Lye MH, Gillen AE, Jordan CT, Singh H, Krause DS, Salomonis N, Grimes HL. Zhang X, et al. Among authors: grimes hl. Nat Immunol. 2024 Apr;25(4):703-715. doi: 10.1038/s41590-024-01782-4. Epub 2024 Mar 21. Nat Immunol. 2024. PMID: 38514887 Free PMC article.
Resilient anatomy and local plasticity of naive and stress haematopoiesis.
Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson CB, Zhang YS, Turcotte R, Alt C, Ito K, Homan S, Sherman BE, Shao TY, Slaughter A, Weinhaus B, Song B, Filippi MD, Grimes HL, Lin CP, Ito K, Way SS, Kofron JM, Lucas D. Wu Q, et al. Among authors: grimes hl. Nature. 2024 Mar;627(8005):839-846. doi: 10.1038/s41586-024-07186-6. Epub 2024 Mar 20. Nature. 2024. PMID: 38509363 Free PMC article.
Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation.
Venkatasubramanian M, Schwartz L, Ramachandra N, Bennett J, Subramanian KR, Chen X, Gordon-Mitchell S, Fromowitz A, Pradhan K, Shechter D, Sahu S, Heiser D, Scherle P, Chetal K, Kulkarni A, Myers KC, Weirauch MT, Grimes HL, Starczynowski DT, Verma A, Salomonis N. Venkatasubramanian M, et al. Among authors: grimes hl. bioRxiv [Preprint]. 2024 Feb 8:2024.02.04.578798. doi: 10.1101/2024.02.04.578798. bioRxiv. 2024. PMID: 38370617 Free PMC article. Preprint.
Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy.
Li G, Mahajan S, Ma S, Jeffery ED, Zhang X, Bhattacharjee A, Venkatasubramanian M, Weirauch MT, Miraldi ER, Grimes HL, Sheynkman GM, Tilburgs T, Salomonis N. Li G, et al. Among authors: grimes hl. Sci Transl Med. 2024 Jan 17;16(730):eade2886. doi: 10.1126/scitranslmed.ade2886. Epub 2024 Jan 17. Sci Transl Med. 2024. PMID: 38232136
Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG).
Ozga M, Nicolet D, Mrózek K, Yilmaz AS, Kohlschmidt J, Larkin KT, Blachly JS, Oakes CC, Buss J, Walker CJ, Orwick S, Jurinovic V, Rothenberg-Thurley M, Dufour A, Schneider S, Sauerland MC, Görlich D, Krug U, Berdel WE, Woermann BJ, Hiddemann W, Braess J, Subklewe M, Spiekermann K, Carroll AJ, Blum WG, Powell BL, Kolitz JE, Moore JO, Mayer RJ, Larson RA, Uy GL, Stock W, Metzeler KH, Grimes HL, Byrd JC, Salomonis N, Herold T, Mims AS, Eisfeld AK. Ozga M, et al. Among authors: grimes hl. Leukemia. 2024 Jan;38(1):45-57. doi: 10.1038/s41375-023-02068-8. Epub 2023 Nov 28. Leukemia. 2024. PMID: 38017103 Free PMC article.
134 results