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Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins.
Mottin M, Caesar LK, Brodsky D, Mesquita NCMR, de Oliveira KZ, Noske GD, Sousa BKP, Ramos PRPS, Jarmer H, Loh B, Zorn KM, Foil DH, Torres PM, Guido RVC, Oliva G, Scholle F, Ekins S, Cech NB, Andrade CH, Laster SM. Mottin M, et al. Among authors: scholle f. Bioorg Chem. 2022 Mar;120:105649. doi: 10.1016/j.bioorg.2022.105649. Epub 2022 Jan 31. Bioorg Chem. 2022. PMID: 35124513 Free PMC article.
Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms.
Puhl AC, Fritch EJ, Lane TR, Tse LV, Yount BL, Sacramento CQ, Fintelman-Rodrigues N, Tavella TA, Maranhão Costa FT, Weston S, Logue J, Frieman M, Premkumar L, Pearce KH, Hurst BL, Andrade CH, Levi JA, Johnson NJ, Kisthardt SC, Scholle F, Souza TML, Moorman NJ, Baric RS, Madrid PB, Ekins S. Puhl AC, et al. Among authors: scholle f. ACS Omega. 2021 Mar 10;6(11):7454-7468. doi: 10.1021/acsomega.0c05996. eCollection 2021 Mar 23. ACS Omega. 2021. PMID: 33778258 Free PMC article.
Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms.
Puhl AC, Fritch EJ, Lane TR, Tse LV, Yount BL, Sacramento CQ, Tavella TA, Costa FTM, Weston S, Logue J, Frieman M, Premkumar L, Pearce KH, Hurst BL, Andrade CH, Levi JA, Johnson NJ, Kisthardt SC, Scholle F, Souza TML, Moorman NJ, Baric RS, Madrid P, Ekins S. Puhl AC, et al. Among authors: scholle f. bioRxiv [Preprint]. 2020 Dec 2:2020.12.01.407361. doi: 10.1101/2020.12.01.407361. bioRxiv. 2020. PMID: 33299990 Free PMC article. Updated. Preprint.
Vandetanib Blocks the Cytokine Storm in SARS-CoV-2-Infected Mice.
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, Lee-Montiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, Dickmander RJ, Baric RS, Pearce KH, Cunha FQ, Alves-Filho JC, Cunha TM, Ekins S. Puhl AC, et al. Among authors: scholle f. ACS Omega. 2022 Aug 29;7(36):31935-31944. doi: 10.1021/acsomega.2c02794. eCollection 2022 Sep 13. ACS Omega. 2022. PMID: 36097511 Free PMC article.
West Nile virus nonstructural protein 1 inhibits TLR3 signal transduction.
Wilson JR, de Sessions PF, Leon MA, Scholle F. Wilson JR, et al. Among authors: scholle f. J Virol. 2008 Sep;82(17):8262-71. doi: 10.1128/JVI.00226-08. Epub 2008 Jun 18. J Virol. 2008. PMID: 18562533 Free PMC article.
We have previously shown that West Nile virus (WNV) is able to inhibit Toll-like receptor 3 (TLR3)-mediated activation of interferon (IFN) regulatory factor 3 (IRF3) (F. Scholle and P. W. Mason, Virology 342:77-87, 2005). In the present study, the WNV nonstructural …
We have previously shown that West Nile virus (WNV) is able to inhibit Toll-like receptor 3 (TLR3)-mediated activation of interferon (IFN) r …
Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model.
Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE Jr, de Silva AM, Ting JP. Callaway JB, et al. Among authors: scholle f. PLoS One. 2015 Aug 24;10(8):e0136708. doi: 10.1371/journal.pone.0136708. eCollection 2015. PLoS One. 2015. PMID: 26301593 Free PMC article.
49 results