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Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology.
Reardon B, Moore ND, Moore NS, Kofman E, AlDubayan SH, Cheung ATM, Conway J, Elmarakeby H, Imamovic A, Kamran SC, Keenan T, Keliher D, Konieczkowski DJ, Liu D, Mouw KW, Park J, Vokes NI, Dietlein F, Van Allen EM. Reardon B, et al. Among authors: konieczkowski dj. Nat Cancer. 2021 Oct;2(10):1102-1112. doi: 10.1038/s43018-021-00243-3. Epub 2021 Sep 30. Nat Cancer. 2021. PMID: 35121878 Free PMC article.
Characterizing genomic alterations in cancer by complementary functional associations.
Kim JW, Botvinnik OB, Abudayyeh O, Birger C, Rosenbluh J, Shrestha Y, Abazeed ME, Hammerman PS, DiCara D, Konieczkowski DJ, Johannessen CM, Liberzon A, Alizad-Rahvar AR, Alexe G, Aguirre A, Ghandi M, Greulich H, Vazquez F, Weir BA, Van Allen EM, Tsherniak A, Shao DD, Zack TI, Noble M, Getz G, Beroukhim R, Garraway LA, Ardakani M, Romualdi C, Sales G, Barbie DA, Boehm JS, Hahn WC, Mesirov JP, Tamayo P. Kim JW, et al. Among authors: konieczkowski dj. Nat Biotechnol. 2016 May;34(5):539-46. doi: 10.1038/nbt.3527. Epub 2016 Apr 18. Nat Biotechnol. 2016. PMID: 27088724 Free PMC article.
Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.
Kim JW, Abudayyeh OO, Yeerna H, Yeang CH, Stewart M, Jenkins RW, Kitajima S, Konieczkowski DJ, Medetgul-Ernar K, Cavazos T, Mah C, Ting S, Van Allen EM, Cohen O, Mcdermott J, Damato E, Aguirre AJ, Liang J, Liberzon A, Alexe G, Doench J, Ghandi M, Vazquez F, Weir BA, Tsherniak A, Subramanian A, Meneses-Cime K, Park J, Clemons P, Garraway LA, Thomas D, Boehm JS, Barbie DA, Hahn WC, Mesirov JP, Tamayo P. Kim JW, et al. Among authors: konieczkowski dj. Cell Syst. 2017 Aug 23;5(2):105-118.e9. doi: 10.1016/j.cels.2017.08.002. Cell Syst. 2017. PMID: 28837809 Free PMC article.
Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer.
Börcsök J, Sztupinszki Z, Bekele R, Gao SP, Diossy M, Samant AS, Dillon KM, Tisza V, Spisák S, Rusz O, Csabai I, Pappot H, Frazier ZJ, Konieczkowski DJ, Liu D, Vasani N, Rodrigues JA, Solit DB, Hoffman-Censits JH, Plimack ER, Rosenberg JE, Lazaro JB, Taplin ME, Iyer G, Brunak S, Lozsa R, Van Allen EM, Szüts D, Mouw KW, Szallasi Z. Börcsök J, et al. Among authors: konieczkowski dj. Clin Cancer Res. 2021 Apr 1;27(7):2011-2022. doi: 10.1158/1078-0432.CCR-20-3316. Epub 2020 Nov 18. Clin Cancer Res. 2021. PMID: 33208343 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 37785455
A Convergence-Based Framework for Cancer Drug Resistance.
Konieczkowski DJ, Johannessen CM, Garraway LA. Konieczkowski DJ, et al. Cancer Cell. 2018 May 14;33(5):801-815. doi: 10.1016/j.ccell.2018.03.025. Cancer Cell. 2018. PMID: 29763622 Free PMC article. Review.
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.
Konieczkowski DJ, Johannessen CM, Abudayyeh O, Kim JW, Cooper ZA, Piris A, Frederick DT, Barzily-Rokni M, Straussman R, Haq R, Fisher DE, Mesirov JP, Hahn WC, Flaherty KT, Wargo JA, Tamayo P, Garraway LA. Konieczkowski DJ, et al. Cancer Discov. 2014 Jul;4(7):816-27. doi: 10.1158/2159-8290.CD-13-0424. Epub 2014 Apr 25. Cancer Discov. 2014. PMID: 24771846 Free PMC article.
MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma.
Wood KC, Konieczkowski DJ, Johannessen CM, Boehm JS, Tamayo P, Botvinnik OB, Mesirov JP, Hahn WC, Root DE, Garraway LA, Sabatini DM. Wood KC, et al. Among authors: konieczkowski dj. Sci Signal. 2012 May 15;5(224):rs4. doi: 10.1126/scisignal.2002612. Sci Signal. 2012. PMID: 22589389 Free PMC article.
33 results