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An adapted consensus protein design strategy for identifying globally optimal biotherapeutics.
Liu Y, Tsang K, Mays M, Hansen G, Chiecko J, Crames M, Wei Y, Zhou W, Fredrick C, Hu J, Liu D, Gebhard D, Huang ZF, Datar A, Kronkaitis A, Gueneva-Boucheva K, Seeliger D, Han F, Sen S, Kasturirangan S, Scheer JM, Nixon AE, Panavas T, Marlow MS, Kumar S. Liu Y, et al. Among authors: scheer jm. MAbs. 2022 Jan-Dec;14(1):2073632. doi: 10.1080/19420862.2022.2073632. MAbs. 2022. PMID: 35613320 Free PMC article.
Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.
Tesar D, Luoma J, Wyatt EA, Shi C, Shatz W, Hass PE, Mathieu M, Yi L, Corn JE, Maass KF, Wang K, Dion MZ, Andersen N, Loyet KM, van Lookeren Campagne M, Rajagopal K, Dickmann L, Scheer JM, Kelley RF. Tesar D, et al. Among authors: scheer jm. MAbs. 2017 Nov/Dec;9(8):1297-1305. doi: 10.1080/19420862.2017.1372078. Epub 2017 Aug 30. MAbs. 2017. PMID: 28854082 Free PMC article.
Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.
Shatz W, Hass PE, Peer N, Paluch MT, Blanchette C, Han G, Sandoval W, Morando A, Loyet KM, Bantseev V, Booler H, Crowell S, Kamath A, Scheer JM, Kelley RF. Shatz W, et al. Among authors: scheer jm. PLoS One. 2019 Jun 28;14(6):e0218613. doi: 10.1371/journal.pone.0218613. eCollection 2019. PLoS One. 2019. PMID: 31251757 Free PMC article.
43 results