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A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity.
Yang J, Wang W, Chen Z, Lu S, Yang F, Bi Z, Bao L, Mo F, Li X, Huang Y, Hong W, Yang Y, Zhao Y, Ye F, Lin S, Deng W, Chen H, Lei H, Zhang Z, Luo M, Gao H, Zheng Y, Gong Y, Jiang X, Xu Y, Lv Q, Li D, Wang M, Li F, Wang S, Wang G, Yu P, Qu Y, Yang L, Deng H, Tong A, Li J, Wang Z, Yang J, Shen G, Zhao Z, Li Y, Luo J, Liu H, Yu W, Yang M, Xu J, Wang J, Li H, Wang H, Kuang D, Lin P, Hu Z, Guo W, Cheng W, He Y, Song X, Chen C, Xue Z, Yao S, Chen L, Ma X, Chen S, Gou M, Huang W, Wang Y, Fan C, Tian Z, Shi M, Wang FS, Dai L, Wu M, Li G, Wang G, Peng Y, Qian Z, Huang C, Lau JY, Yang Z, Wei Y, Cen X, Peng X, Qin C, Zhang K, Lu G, Wei X. Yang J, et al. Among authors: yang f, yang l, yang m, yang y, yang z. Nature. 2020 Oct;586(7830):572-577. doi: 10.1038/s41586-020-2599-8. Epub 2020 Jul 29. Nature. 2020. PMID: 32726802
Susceptibility of tree shrew to SARS-CoV-2 infection.
Zhao Y, Wang J, Kuang D, Xu J, Yang M, Ma C, Zhao S, Li J, Long H, Ding K, Gao J, Liu J, Wang H, Li H, Yang Y, Yu W, Yang J, Zheng Y, Wu D, Lu S, Liu H, Peng X. Zhao Y, et al. Among authors: yang m, yang y, yang j. Sci Rep. 2020 Sep 29;10(1):16007. doi: 10.1038/s41598-020-72563-w. Sci Rep. 2020. PMID: 32994418 Free PMC article.
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models.
Wang G, Yang ML, Duan ZL, Liu FL, Jin L, Long CB, Zhang M, Tang XP, Xu L, Li YC, Kamau PM, Yang L, Liu HQ, Xu JW, Chen JK, Zheng YT, Peng XZ, Lai R. Wang G, et al. Among authors: yang l, yang ml. Cell Res. 2021 Jan;31(1):17-24. doi: 10.1038/s41422-020-00450-0. Epub 2020 Dec 1. Cell Res. 2021. PMID: 33262453 Free PMC article.
Antibody response elicited by a third boost dose of inactivated SARS-CoV-2 vaccine can neutralize SARS-CoV-2 variants of concern.
Yue L, Zhou J, Zhou Y, Yang X, Xie T, Yang M, Zhao H, Zhao Y, Yang T, Li H, Xiang H, Wang J, Lu S, Liu H, Zhao H, Wei X, Zhang Y, Xie Z. Yue L, et al. Among authors: yang t, yang m, yang x. Emerg Microbes Infect. 2021 Dec;10(1):2125-2127. doi: 10.1080/22221751.2021.1996210. Emerg Microbes Infect. 2021. PMID: 34666622 Free PMC article. No abstract available.
Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells.
Hong W, Yang J, Zou J, Bi Z, He C, Lei H, He X, Li X, Alu A, Ren W, Wang Z, Jiang X, Zhong K, Jia G, Yang Y, Yu W, Huang Q, Yang M, Zhou Y, Zhao Y, Kuang D, Wang J, Wang H, Chen S, Luo M, Zhang Z, Lu T, Chen L, Que H, He Z, Sun Q, Wang W, Shen G, Lu G, Zhao Z, Yang L, Yang J, Wang Z, Li J, Song X, Dai L, Chen C, Geng J, Gou M, Chen L, Dong H, Peng Y, Huang C, Qian Z, Cheng W, Fan C, Wei Y, Su Z, Tong A, Lu S, Peng X, Wei X. Hong W, et al. Among authors: yang l, yang m, yang y, yang j. Cell Mol Immunol. 2022 May;19(5):577-587. doi: 10.1038/s41423-022-00845-6. Epub 2022 Mar 10. Cell Mol Immunol. 2022. PMID: 35273357 Free PMC article.
Polymerized porin as a novel delivery platform for coronavirus vaccine.
Yang Z, Hua L, Yang M, Li W, Ren Z, Zheng X, Chen H, Long Q, Bai H, Huang W, Ma Y. Yang Z, et al. Among authors: yang m. J Nanobiotechnology. 2022 Jun 7;20(1):260. doi: 10.1186/s12951-022-01469-8. J Nanobiotechnology. 2022. PMID: 35672856 Free PMC article.
A self-assembled trimeric protein vaccine induces protective immunity against Omicron variant.
He C, Yang J, Hong W, Chen Z, Peng D, Lei H, Alu A, He X, Bi Z, Jiang X, Jia G, Yang Y, Zhou Y, Yu W, Tang C, Huang Q, Yang M, Li B, Li J, Wang J, Que H, Chen L, Ren W, Wan D, Li J, Wang W, Shen G, Zhao Z, Yang L, Yang J, Wang Z, Su Z, Wei Y, Cen X, Tanaka Y, Song X, Lu S, Peng X, Lu G, Wei X. He C, et al. Among authors: yang l, yang m, yang y, yang j. Nat Commun. 2022 Sep 17;13(1):5459. doi: 10.1038/s41467-022-33209-9. Nat Commun. 2022. PMID: 36115859 Free PMC article.
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice.
Bao L, Deng W, Huang B, Gao H, Liu J, Ren L, Wei Q, Yu P, Xu Y, Qi F, Qu Y, Li F, Lv Q, Wang W, Xue J, Gong S, Liu M, Wang G, Wang S, Song Z, Zhao L, Liu P, Zhao L, Ye F, Wang H, Zhou W, Zhu N, Zhen W, Yu H, Zhang X, Guo L, Chen L, Wang C, Wang Y, Wang X, Xiao Y, Sun Q, Liu H, Zhu F, Ma C, Yan L, Yang M, Han J, Xu W, Tan W, Peng X, Jin Q, Wu G, Qin C. Bao L, et al. Among authors: yang m. Nature. 2020 Jul;583(7818):830-833. doi: 10.1038/s41586-020-2312-y. Epub 2020 May 7. Nature. 2020. PMID: 32380511
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