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RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
Carnevale J, Shifrut E, Kale N, Nyberg WA, Blaeschke F, Chen YY, Li Z, Bapat SP, Diolaiti ME, O'Leary P, Vedova S, Belk J, Daniel B, Roth TL, Bachl S, Anido AA, Prinzing B, Ibañez-Vega J, Lange S, Haydar D, Luetke-Eversloh M, Born-Bony M, Hegde B, Kogan S, Feuchtinger T, Okada H, Satpathy AT, Shannon K, Gottschalk S, Eyquem J, Krenciute G, Ashworth A, Marson A. Carnevale J, et al. Nature. 2022 Sep;609(7925):174-182. doi: 10.1038/s41586-022-05126-w. Epub 2022 Aug 24. Nature. 2022. PMID: 36002574 Free PMC article.
Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling.
Bell M, Lange S, Sejdiu BI, Ibanez J, Shi H, Sun X, Meng X, Nguyen P, Sutton M, Wagner J, Kc A, Langfitt D, Patil SL, Tan H, Pandey RV, Li Y, Yuan ZF, Anido AA, Ho M, Sheppard H, Vogel P, Yu J, Peng J, Chi H, Babu MM, Krenciute G, Gottschalk S. Bell M, et al. Nat Biomed Eng. 2024 Apr;8(4):380-396. doi: 10.1038/s41551-023-01143-w. Epub 2023 Nov 30. Nat Biomed Eng. 2024. PMID: 38036617
A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function.
Lange S, Sand LGL, Bell M, Patil SL, Langfitt D, Gottschalk S. Lange S, et al. Cancer Discov. 2021 Jul;11(7):1661-1671. doi: 10.1158/2159-8290.CD-20-0896. Epub 2021 Feb 9. Cancer Discov. 2021. PMID: 33563660 Free PMC article.
Correction: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
Armstrong LA, Lange SM, Cesare V, Matthews SP, Nirujogi RS, Cole I, Hope A, Cunningham F, Toth R, Mukherjee R, Bojkova D, Gruber F, Gray D, Wyatt PG, Cinatl J, Dikic I, Davies P, Kulathu Y. Armstrong LA, et al. Among authors: lange sm. PLoS One. 2024 Apr 16;19(4):e0302418. doi: 10.1371/journal.pone.0302418. eCollection 2024. PLoS One. 2024. PMID: 38626090 Free PMC article.
Collagen Vascular Disease Associated With Interstitial Lung.
Lange SM, Sankari A, Parekh M. Lange SM, et al. 2024 Feb 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2024 Feb 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32644520 Free Books & Documents.
UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.
Barnsby-Greer L, Mabbitt PD, Dery MA, Squair DR, Wood NT, Lamoliatte F, Lange SM, Virdee S. Barnsby-Greer L, et al. Among authors: lange sm. Nat Struct Mol Biol. 2024 Feb;31(2):351-363. doi: 10.1038/s41594-023-01192-4. Epub 2024 Jan 5. Nat Struct Mol Biol. 2024. PMID: 38182926 Free PMC article.
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