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Co-administration of Favipiravir and the Remdesivir Metabolite GS-441524 Effectively Reduces SARS-CoV-2 Replication in the Lungs of the Syrian Hamster Model.
Chiba S, Kiso M, Nakajima N, Iida S, Maemura T, Kuroda M, Sato Y, Ito M, Okuda M, Yamada S, Iwatsuki-Horimoto K, Watanabe T, Imai M, Armbrust T, Baric RS, Halfmann PJ, Suzuki T, Kawaoka Y. Chiba S, et al. Among authors: kuroda m. mBio. 2021 Feb 22;13(1):e0304421. doi: 10.1128/mbio.03044-21. Epub 2022 Feb 1. mBio. 2021. PMID: 35100870 Free PMC article.
The first autopsy case of pandemic influenza (A/H1N1pdm) virus infection in Japan: detection of a high copy number of the virus in type II alveolar epithelial cells by pathological and virological examination.
Nakajima N, Hata S, Sato Y, Tobiume M, Katano H, Kaneko K, Nagata N, Kataoka M, Ainai A, Hasegawa H, Tashiro M, Kuroda M, Odai T, Urasawa N, Ogino T, Hanaoka H, Watanabe M, Sata T. Nakajima N, et al. Among authors: kuroda m. Jpn J Infect Dis. 2010 Jan;63(1):67-71. Jpn J Infect Dis. 2010. PMID: 20093768
The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.
Sakai K, Ami Y, Tahara M, Kubota T, Anraku M, Abe M, Nakajima N, Sekizuka T, Shirato K, Suzaki Y, Ainai A, Nakatsu Y, Kanou K, Nakamura K, Suzuki T, Komase K, Nobusawa E, Maenaka K, Kuroda M, Hasegawa H, Kawaoka Y, Tashiro M, Takeda M. Sakai K, et al. Among authors: kuroda m. J Virol. 2014 May;88(10):5608-16. doi: 10.1128/JVI.03677-13. Epub 2014 Mar 5. J Virol. 2014. PMID: 24600012 Free PMC article.
A mutant H3N2 influenza virus uses an alternative activation mechanism in TMPRSS2 knockout mice by loss of an oligosaccharide in the hemagglutinin stalk region.
Sakai K, Sekizuka T, Ami Y, Nakajima N, Kitazawa M, Sato Y, Nakajima K, Anraku M, Kubota T, Komase K, Takehara K, Hasegawa H, Odagiri T, Tashiro M, Kuroda M, Takeda M. Sakai K, et al. Among authors: kuroda m. J Virol. 2015 May;89(9):5154-8. doi: 10.1128/JVI.00124-15. Epub 2015 Feb 11. J Virol. 2015. PMID: 25673722 Free PMC article.
Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells.
Matsuyama S, Nao N, Shirato K, Kawase M, Saito S, Takayama I, Nagata N, Sekizuka T, Katoh H, Kato F, Sakata M, Tahara M, Kutsuna S, Ohmagari N, Kuroda M, Suzuki T, Kageyama T, Takeda M. Matsuyama S, et al. Among authors: kuroda m. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7001-7003. doi: 10.1073/pnas.2002589117. Epub 2020 Mar 12. Proc Natl Acad Sci U S A. 2020. PMID: 32165541 Free PMC article.
Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan.
Adachi T, Chong JM, Nakajima N, Sano M, Yamazaki J, Miyamoto I, Nishioka H, Akita H, Sato Y, Kataoka M, Katano H, Tobiume M, Sekizuka T, Itokawa K, Kuroda M, Suzuki T. Adachi T, et al. Among authors: kuroda m. Emerg Infect Dis. 2020 Sep;26(9):2157-61. doi: 10.3201/eid2609.201353. Epub 2020 May 15. Emerg Infect Dis. 2020. PMID: 32412897 Free PMC article.
2,268 results