Sim KS - Search Results

1

Antiproliferative and Microtubule-stabilizing Activities of Two Iboga-vobasine Bisindoles Alkaloids from Tabernaemontana corymbosa in Colorectal Adenocarcinoma HT-29 Cells.

Tan CH, Sim DSY, Lim SH, Mohd Mohidin TB, Mohan G, Low YY, Kam TS, Sim KS. Tan CH, et al. Among authors: sim ks, sim dsy. Planta Med. 2022 Nov;88(14):1325-1340. doi: 10.1055/a-1755-5605. Epub 2022 Jan 31. Planta Med. 2022. PMID: 35100653

2

Cytotoxic vobasine, tacaman, and corynanthe-tryptamine bisindole alkaloids from Tabernaemontana and structure revision of tronoharine.

Sim DS, Chong KW, Nge CE, Low YY, Sim KS, Kam TS. Sim DS, et al. Among authors: sim ks. J Nat Prod. 2014 Nov 26;77(11):2504-12. doi: 10.1021/np500589u. Epub 2014 Oct 21. J Nat Prod. 2014. PMID: 25333996

3

Vobatensines A-F, Cytotoxic Iboga-Vobasine Bisindoles from Tabernaemontana corymbosa.

Sim DS, Teoh WY, Sim KS, Lim SH, Thomas NF, Low YY, Kam TS. Sim DS, et al. Among authors: sim ks. J Nat Prod. 2016 Apr 22;79(4):1048-55. doi: 10.1021/acs.jnatprod.5b01117. Epub 2016 Feb 26. J Nat Prod. 2016. PMID: 26918761

4

Conolodinines A-D, Aspidosperma- Aspidosperma Bisindole Alkaloids with Antiproliferative Activity from Tabernaemontana corymbosa.

Sim DS, Navanesan S, Sim KS, Gurusamy S, Lim SH, Low YY, Kam TS. Sim DS, et al. Among authors: sim ks. J Nat Prod. 2019 Apr 26;82(4):850-858. doi: 10.1021/acs.jnatprod.8b00919. Epub 2019 Mar 14. J Nat Prod. 2019. PMID: 30869890

5

Structural insights and cytotoxicity evaluation of benz[e]indole pyrazolyl-substituted amides.

Ramle AQ, Chan NNMY, Ng MP, Tan CH, Sim KS, Tiekink ERT, Fei CC. Ramle AQ, et al. Among authors: sim ks. Mol Divers. 2023 Jun 6. doi: 10.1007/s11030-023-10662-2. Online ahead of print. Mol Divers. 2023. PMID: 37278911

6

Discovery of indoleninyl-pyrazolo[3,4-b]pyridines as potent chemotherapeutic agents against colorectal cancer cells.

Basir NH, Ramle AQ, Ng MP, Tan CH, Tiekink ERT, Sim KS, Basirun WJ, Khairuddean M. Basir NH, et al. Among authors: sim ks. Bioorg Chem. 2024 May;146:107256. doi: 10.1016/j.bioorg.2024.107256. Epub 2024 Mar 2. Bioorg Chem. 2024. PMID: 38460334

7

The Bisindole Alkaloids Angustilongines M and A from Alstonia penangiana Induce Mitochondrial Apoptosis and G0/G1 Cell Cycle Arrest in HT-29 Cells through Promotion of Tubulin Polymerization.

Tan CH, Yeap JS, Lim SH, Low YY, Sim KS, Kam TS. Tan CH, et al. Among authors: sim ks. J Nat Prod. 2021 May 28;84(5):1524-1533. doi: 10.1021/acs.jnatprod.1c00013. Epub 2021 Apr 19. J Nat Prod. 2021. PMID: 33872002

8

Polyneurines A-H, iboga alkaloids from Tabernaemontana polyneura.

Tang SY, Tan CH, Sim KS, Yong KT, Lim KH, Low YY, Lim SH. Tang SY, et al. Among authors: sim ks. Phytochemistry. 2023 Apr;208:113587. doi: 10.1016/j.phytochem.2023.113587. Epub 2023 Jan 14. Phytochemistry. 2023. PMID: 36646163

9

A Hexacyclic, Iboga-Derived Monoterpenoid Indole with a Contracted Tetrahydroazepine C-Ring and Incorporation of an Isoxazolidine Moiety, a Seco-Corynanthean, an Aspidosperma-Aspidosperma Bisindole with Anticancer Properties, and the Absolute Configuration of the Pyridopyrimidine Indole Alkaloid, Vernavosine.

Nge CE, Sim KS, Lim SH, Thomas NF, Low YY, Kam TS. Nge CE, et al. Among authors: sim ks. J Nat Prod. 2016 Oct 28;79(10):2709-2717. doi: 10.1021/acs.jnatprod.6b00674. Epub 2016 Oct 19. J Nat Prod. 2016. PMID: 27759387

10

Antiproliferation effect of guanosine on HCT 116 cells involves MAPK and AMPK pathways.

Teoh WY, Wahab NA, Sim KS. Teoh WY, et al. Among authors: sim ks. Nucleosides Nucleotides Nucleic Acids. 2017 Apr 3;36(4):243-255. doi: 10.1080/15257770.2016.1268693. Epub 2017 Mar 21. Nucleosides Nucleotides Nucleic Acids. 2017. PMID: 28323520

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