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Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators.
Amin OE, Colbeck EJ, Daffis S, Khan S, Ramakrishnan D, Pattabiraman D, Chu R, Micolochick Steuer H, Lehar S, Peiser L, Palazzo A, Frey C, Davies J, Javanbakht H, Rosenberg WMC, Fletcher SP, Maini MK, Pallett LJ. Amin OE, et al. Among authors: javanbakht h. Hepatology. 2021 Jul;74(1):55-71. doi: 10.1002/hep.31695. Epub 2021 Jun 20. Hepatology. 2021. PMID: 33368377 Free PMC article. Clinical Trial.
Host RNA quality control as a hepatitis B antiviral target.
Block TM, Young JAT, Javanbakht H, Sofia MJ, Zhou T. Block TM, et al. Among authors: javanbakht h. Antiviral Res. 2021 Feb;186:104972. doi: 10.1016/j.antiviral.2020.104972. Epub 2020 Nov 24. Antiviral Res. 2021. PMID: 33242518 Review.
Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon-α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus.
Menne S, Wildum S, Steiner G, Suresh M, Korolowicz K, Balarezo M, Yon C, Murreddu M, Hong X, Kallakury BV, Tucker R, Yang S, Young JAT, Javanbakht H. Menne S, et al. Among authors: javanbakht h. Hepatol Commun. 2020 Apr 22;4(6):916-931. doi: 10.1002/hep4.1502. eCollection 2020 Jun. Hepatol Commun. 2020. PMID: 32490326 Free PMC article.
Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action.
Han X, Zhou C, Jiang M, Wang Y, Wang J, Cheng Z, Wang M, Liu Y, Liang C, Wang J, Wang Z, Weikert R, Lv W, Xie J, Yu X, Zhou X, Luangsay S, Shen HC, Mayweg AV, Javanbakht H, Yang S. Han X, et al. Among authors: javanbakht h. J Med Chem. 2018 Dec 13;61(23):10619-10634. doi: 10.1021/acs.jmedchem.8b01245. Epub 2018 Oct 17. J Med Chem. 2018. PMID: 30286292
56 results