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71 results

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Page 1
Expanding Therapeutic Opportunities for Extrapulmonary Neuroendocrine Carcinoma.
Frizziero M, Kilgour E, Simpson KL, Rothwell DG, Moore DA, Frese KK, Galvin M, Lamarca A, Hubner RA, Valle JW, McNamara MG, Dive C. Frizziero M, et al. Among authors: rothwell dg. Clin Cancer Res. 2022 May 13;28(10):1999-2019. doi: 10.1158/1078-0432.CCR-21-3058. Clin Cancer Res. 2022. PMID: 35091446 Free PMC article. Review.
Eotaxin-2 and colorectal cancer: a potential target for immune therapy.
Cheadle EJ, Riyad K, Subar D, Rothwell DG, Ashton G, Batha H, Sherlock DJ, Hawkins RE, Gilham DE. Cheadle EJ, et al. Among authors: rothwell dg. Clin Cancer Res. 2007 Oct 1;13(19):5719-28. doi: 10.1158/1078-0432.CCR-07-1145. Clin Cancer Res. 2007. PMID: 17908961
The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity.
Thistlethwaite FC, Gilham DE, Guest RD, Rothwell DG, Pillai M, Burt DJ, Byatte AJ, Kirillova N, Valle JW, Sharma SK, Chester KA, Westwood NB, Halford SER, Nabarro S, Wan S, Austin E, Hawkins RE. Thistlethwaite FC, et al. Among authors: rothwell dg. Cancer Immunol Immunother. 2017 Nov;66(11):1425-1436. doi: 10.1007/s00262-017-2034-7. Epub 2017 Jun 28. Cancer Immunol Immunother. 2017. PMID: 28660319 Free PMC article. Clinical Trial.
Molecular analysis of single circulating tumour cells following long-term storage of clinical samples.
Mesquita B, Rothwell DG, Burt DJ, Chemi F, Fernandez-Gutierrez F, Slane-Tan D, Antonello J, Carter M, Carter L, Parry M, Franklin L, Marais R, Blackhall F, Dive C, Brady G. Mesquita B, et al. Among authors: rothwell dg. Mol Oncol. 2017 Dec;11(12):1687-1697. doi: 10.1002/1878-0261.12113. Epub 2017 Oct 24. Mol Oncol. 2017. PMID: 28741788 Free PMC article.
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
McGranahan N, Rosenthal R, Hiley CT, Rowan AJ, Watkins TBK, Wilson GA, Birkbak NJ, Veeriah S, Van Loo P, Herrero J, Swanton C; TRACERx Consortium. McGranahan N, et al. Cell. 2017 Nov 30;171(6):1259-1271.e11. doi: 10.1016/j.cell.2017.10.001. Epub 2017 Oct 26. Cell. 2017. PMID: 29107330 Free PMC article.
In silico error correction improves cfDNA mutation calling.
Kim CS, Mohan S, Ayub M, Rothwell DG, Dive C, Brady G, Miller C. Kim CS, et al. Among authors: rothwell dg. Bioinformatics. 2019 Jul 15;35(14):2380-2385. doi: 10.1093/bioinformatics/bty1004. Bioinformatics. 2019. PMID: 30520956 Free PMC article.
Neoantigen-directed immune escape in lung cancer evolution.
Rosenthal R, Cadieux EL, Salgado R, Bakir MA, Moore DA, Hiley CT, Lund T, Tanić M, Reading JL, Joshi K, Henry JY, Ghorani E, Wilson GA, Birkbak NJ, Jamal-Hanjani M, Veeriah S, Szallasi Z, Loi S, Hellmann MD, Feber A, Chain B, Herrero J, Quezada SA, Demeulemeester J, Van Loo P, Beck S, McGranahan N, Swanton C; TRACERx consortium. Rosenthal R, et al. Nature. 2019 Mar;567(7749):479-485. doi: 10.1038/s41586-019-1032-7. Epub 2019 Mar 20. Nature. 2019. PMID: 30894752 Free PMC article.
Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study.
Rothwell DG, Ayub M, Cook N, Thistlethwaite F, Carter L, Dean E, Smith N, Villa S, Dransfield J, Clipson A, White D, Nessa K, Ferdous S, Howell M, Gupta A, Kilerci B, Mohan S, Frese K, Gulati S, Miller C, Jordan A, Eaton H, Hickson N, O'Brien C, Graham D, Kelly C, Aruketty S, Metcalf R, Chiramel J, Tinsley N, Vickers AJ, Kurup R, Frost H, Stevenson J, Southam S, Landers D, Wallace A, Marais R, Hughes AM, Brady G, Dive C, Krebs MG. Rothwell DG, et al. Nat Med. 2019 May;25(5):738-743. doi: 10.1038/s41591-019-0380-z. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011204 Free article.
Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer.
Mohan S, Ayub M, Rothwell DG, Gulati S, Kilerci B, Hollebecque A, Sun Leong H, Smith NK, Sahoo S, Descamps T, Zhou C, Hubner RA, McNamara MG, Lamarca A, Valle JW, Dive C, Brady G. Mohan S, et al. Among authors: rothwell dg. Sci Rep. 2019 Aug 12;9(1):11610. doi: 10.1038/s41598-019-47489-7. Sci Rep. 2019. PMID: 31406261 Free PMC article.
71 results