Metformin treatment improves the spatial memory of aged mice in an APOE genotype-dependent manner.
Zhang J, Lin Y, Dai X, Fang W, Wu X, Chen X.
Zhang J, et al.
FASEB J. 2019 Jun;33(6):7748-7757. doi: 10.1096/fj.201802718R. Epub 2019 Mar 20.
FASEB J. 2019.
PMID: 30894020
These findings suggest that metformin can improve the cognitive performance of aged mice in an APOE genotype-dependent manner, which provides empirical insights into the clinical value of metformin for ApoE4- and age-related AD prevention and treatment.-Zhang, J., L …
These findings suggest that metformin can improve the cognitive performance of aged mice in an APOE genotype-dependent manner, which provide …