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Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter.
Miedema A, Gerrits E, Brouwer N, Jiang Q, Kracht L, Meijer M, Nutma E, Peferoen-Baert R, Pijnacker ATE, Wesseling EM, Wijering MHC, Gabius HJ, Amor S, Eggen BJL, Kooistra SM. Miedema A, et al. Among authors: brouwer n. Acta Neuropathol Commun. 2022 Jan 28;10(1):8. doi: 10.1186/s40478-021-01306-3. Acta Neuropathol Commun. 2022. PMID: 35090578 Free PMC article.
Priming of microglia in a DNA-repair deficient model of accelerated aging.
Raj DD, Jaarsma D, Holtman IR, Olah M, Ferreira FM, Schaafsma W, Brouwer N, Meijer MM, de Waard MC, van der Pluijm I, Brandt R, Kreft KL, Laman JD, de Haan G, Biber KP, Hoeijmakers JH, Eggen BJ, Boddeke HW. Raj DD, et al. Among authors: brouwer n. Neurobiol Aging. 2014 Sep;35(9):2147-60. doi: 10.1016/j.neurobiolaging.2014.03.025. Epub 2014 Mar 28. Neurobiol Aging. 2014. PMID: 24799273 Free article.
Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing.
Schaafsma W, Zhang X, van Zomeren KC, Jacobs S, Georgieva PB, Wolf SA, Kettenmann H, Janova H, Saiepour N, Hanisch UK, Meerlo P, van den Elsen PJ, Brouwer N, Boddeke HW, Eggen BJ. Schaafsma W, et al. Among authors: brouwer n. Brain Behav Immun. 2015 Aug;48:205-21. doi: 10.1016/j.bbi.2015.03.013. Epub 2015 Apr 2. Brain Behav Immun. 2015. PMID: 25843371
149 results