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Regulation of insulin gene transcription.
Stein R. Stein R. Trends Endocrinol Metab. 1993 Apr;4(3):96-101. doi: 10.1016/1043-2760(93)90086-t. Trends Endocrinol Metab. 1993. PMID: 18407141
MafA is a dedicated activator of the insulin gene in vivo.
Artner I, Hang Y, Guo M, Gu G, Stein R. Artner I, et al. Among authors: stein r. J Endocrinol. 2008 Aug;198(2):271-9. doi: 10.1677/JOE-08-0063. Epub 2008 May 30. J Endocrinol. 2008. PMID: 18515495 Free PMC article.
MafA and MafB activity in pancreatic β cells.
Hang Y, Stein R. Hang Y, et al. Among authors: stein r. Trends Endocrinol Metab. 2011 Sep;22(9):364-73. doi: 10.1016/j.tem.2011.05.003. Epub 2011 Jun 28. Trends Endocrinol Metab. 2011. PMID: 21719305 Free PMC article. Review.
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Conrad E, Dai C, Spaeth J, Guo M, Cyphert HA, Scoville D, Carroll J, Yu WM, Goodrich LV, Harlan DM, Grove KL, Roberts CT Jr, Powers AC, Gu G, Stein R. Conrad E, et al. Among authors: stein r. Am J Physiol Endocrinol Metab. 2016 Jan 1;310(1):E91-E102. doi: 10.1152/ajpendo.00285.2015. Epub 2015 Nov 10. Am J Physiol Endocrinol Metab. 2016. PMID: 26554594 Free PMC article.
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.
Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. Brissova M, et al. Among authors: stein r. Cell Rep. 2018 Mar 6;22(10):2667-2676. doi: 10.1016/j.celrep.2018.02.032. Cell Rep. 2018. PMID: 29514095 Free PMC article.
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.
Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, Stein RW, Brissova M, Powers AC. Haliyur R, et al. Among authors: stein rw. J Clin Invest. 2019 Jan 2;129(1):246-251. doi: 10.1172/JCI121994. Epub 2018 Dec 3. J Clin Invest. 2019. PMID: 30507613 Free PMC article.
3,069 results