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The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent.
Cancer Chemother Pharmacol. 2023 May;91(5):401-412. doi: 10.1007/s00280-023-04528-5. Epub 2023 Mar 31.
Cancer Chemother Pharmacol. 2023.
PMID: 37000221
Free PMC article.
Heparanase-1 is upregulated by hepatitis C virus and favors its replication.
Gallard C, Lebsir N, Khursheed H, Reungoat E, Plissonnier ML, Bré J, Michelet M, Chouik Y, Zoulim F, Pécheur EI, Bartosch B, Grigorov B.
Gallard C, et al. Among authors: bre j.
J Hepatol. 2022 Jul;77(1):29-41. doi: 10.1016/j.jhep.2022.01.008. Epub 2022 Jan 25.
J Hepatol. 2022.
PMID: 35085593
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Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031.
Sarr A, Bré J, Um IH, Chan TH, Mullen P, Harrison DJ, Reynolds PA.
Sarr A, et al. Among authors: bre j.
Sci Rep. 2019 May 21;9(1):7643. doi: 10.1038/s41598-019-44089-3.
Sci Rep. 2019.
PMID: 31113993
Free PMC article.
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Reduced growth of Listeria monocytogenes in two model cheese microcosms is not associated with individual microbial strains.
Imran M, Bré JM, Guéguen M, Vernoux JP, Desmasures N.
Imran M, et al. Among authors: bre jm.
Food Microbiol. 2013 Feb;33(1):30-9. doi: 10.1016/j.fm.2012.08.008. Epub 2012 Sep 14.
Food Microbiol. 2013.
PMID: 23122498
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