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Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy.
Uldrick TS, Adams SV, Fromentin R, Roche M, Fling SP, Gonçalves PH, Lurain K, Ramaswami R, Wang CJ, Gorelick RJ, Welker JL, O'Donoghue L, Choudhary H, Lifson JD, Rasmussen TA, Rhodes A, Tumpach C, Yarchoan R, Maldarelli F, Cheever MA, Sékaly R, Chomont N, Deeks SG, Lewin SR. Uldrick TS, et al. Among authors: sekaly r. Sci Transl Med. 2022 Jan 26;14(629):eabl3836. doi: 10.1126/scitranslmed.abl3836. Epub 2022 Jan 26. Sci Transl Med. 2022. PMID: 35080914 Free PMC article.
Combination Immune Checkpoint Blockade to Reverse HIV Latency.
Van der Sluis RM, Kumar NA, Pascoe RD, Zerbato JM, Evans VA, Dantanarayana AI, Anderson JL, Sékaly RP, Fromentin R, Chomont N, Cameron PU, Lewin SR. Van der Sluis RM, et al. Among authors: sekaly rp. J Immunol. 2020 Mar 1;204(5):1242-1254. doi: 10.4049/jimmunol.1901191. Epub 2020 Jan 27. J Immunol. 2020. PMID: 31988180 Free PMC article.
Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs.
Katlama C, Deeks SG, Autran B, Martinez-Picado J, van Lunzen J, Rouzioux C, Miller M, Vella S, Schmitz JE, Ahlers J, Richman DD, Sekaly RP. Katlama C, et al. Lancet. 2013 Jun 15;381(9883):2109-17. doi: 10.1016/S0140-6736(13)60104-X. Epub 2013 Mar 29. Lancet. 2013. PMID: 23541541 Free PMC article. Review.
Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART.
Pino M, Pereira Ribeiro S, Pagliuzza A, Ghneim K, Khan A, Ryan E, Harper JL, King CT, Welbourn S, Micci L, Aldrete S, Delman KA, Stuart T, Lowe M, Brenchley JM, Derdeyn CA, Easley K, Sekaly RP, Chomont N, Paiardini M, Marconi VC. Pino M, et al. PLoS Pathog. 2021 Aug 27;17(8):e1009825. doi: 10.1371/journal.ppat.1009825. eCollection 2021 Aug. PLoS Pathog. 2021. PMID: 34449812 Free PMC article.
A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"?
Lederman MM, Cannon PM, Currier JS, June CH, Kiem HP, Kuritzkes DR, Lewin SR, Margolis DM, McCune JM, Mellors JW, Schacker TW, Sekaly RP, Tebas P, Walker BD, Douek DC. Lederman MM, et al. Among authors: sekaly rp. Pathog Immun. 2016 Spring;1(1):154-164. doi: 10.20411/pai.v1i1.133. Pathog Immun. 2016. PMID: 27668293 Free PMC article.
Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody.
Asokan M, Dias J, Liu C, Maximova A, Ernste K, Pegu A, McKee K, Shi W, Chen X, Almasri C, Promsote W, Ambrozak DR, Gama L, Hu J, Douek DC, Todd JP, Lifson JD, Fourati S, Sekaly RP, Crowley AR, Ackerman ME, Ko SH, Kilam D, Boritz EA, Liao LE, Best K, Perelson AS, Mascola JR, Koup RA. Asokan M, et al. Among authors: sekaly rp. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18754-18763. doi: 10.1073/pnas.2008236117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690707 Free PMC article.
A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials.
Ehrenberg PK, Shangguan S, Issac B, Alter G, Geretz A, Izumi T, Bryant C, Eller MA, Wegmann F, Apps R, Creegan M, Bolton DL, Sekaly RP, Robb ML, Gramzinski RA, Pau MG, Schuitemaker H, Barouch DH, Michael NL, Thomas R. Ehrenberg PK, et al. Among authors: sekaly rp. Sci Transl Med. 2019 Aug 28;11(507):eaaw4236. doi: 10.1126/scitranslmed.aaw4236. Sci Transl Med. 2019. PMID: 31462510 Free PMC article.
409 results