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T cell subtype profiling measures exhaustion and predicts anti-PD-1 response.
Schillebeeckx I, Earls J, Flanagan KC, Hiken J, Bode A, Armstrong JR, Messina DN, Adkins D, Ley J, Alborelli I, Jermann P, Glasscock JI. Schillebeeckx I, et al. Among authors: earls j. Sci Rep. 2022 Jan 25;12(1):1342. doi: 10.1038/s41598-022-05474-7. Sci Rep. 2022. PMID: 35079117 Free PMC article.
Analytical Performance of an Immunoprofiling Assay Based on RNA Models.
Schillebeeckx I, Armstrong JR, Forys JT, Hiken J, Earls J, Flanagan KC, Cui T, Glasscock JI, Messina DN, Duncavage EJ. Schillebeeckx I, et al. Among authors: earls j. J Mol Diagn. 2020 Apr;22(4):555-570. doi: 10.1016/j.jmoldx.2020.01.009. Epub 2020 Feb 7. J Mol Diagn. 2020. PMID: 32036085 Free article.
Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells.
Goff PH, Riolobos L, LaFleur BJ, Spraker MB, Seo YD, Smythe KS, Campbell JS, Pierce RH, Zhang Y, He Q, Kim EY, Schaub SK, Kane GM, Mantilla JG, Chen EY, Ricciotti R, Thompson MJ, Cranmer LD, Wagner MJ, Loggers ET, Jones RL, Murphy E, Blumenschein WM, McClanahan TK, Earls J, Flanagan KC, LaFranzo NA, Kim TS, Pollack SM. Goff PH, et al. Among authors: earls j. Clin Cancer Res. 2022 Apr 14;28(8):1701-1711. doi: 10.1158/1078-0432.CCR-21-4239. Clin Cancer Res. 2022. PMID: 35115306 Free PMC article.
Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW, Martin ER, Naj AC, Ertekin-Taner N, Golde TE, Hood L, Price ND; Alzheimer’s Disease Genetics Consortium. Heath L, et al. Sci Rep. 2022 Apr 12;12(1):6117. doi: 10.1038/s41598-022-09825-2. Sci Rep. 2022. PMID: 35413975 Free PMC article.
A wellness study of 108 individuals using personal, dense, dynamic data clouds.
Price ND, Magis AT, Earls JC, Glusman G, Levy R, Lausted C, McDonald DT, Kusebauch U, Moss CL, Zhou Y, Qin S, Moritz RL, Brogaard K, Omenn GS, Lovejoy JC, Hood L. Price ND, et al. Nat Biotechnol. 2017 Aug;35(8):747-756. doi: 10.1038/nbt.3870. Epub 2017 Jul 17. Nat Biotechnol. 2017. PMID: 28714965 Free PMC article.
Reply to "Precision medicine in the clouds".
Magis AT, Earls JC, Glusman G, Omenn GS, Lovejoy JC, Price ND, Hood L. Magis AT, et al. Nat Biotechnol. 2018 Aug 6;36(8):680-682. doi: 10.1038/nbt.4211. Nat Biotechnol. 2018. PMID: 30080845 No abstract available.
Blood metabolome predicts gut microbiome α-diversity in humans.
Wilmanski T, Rappaport N, Earls JC, Magis AT, Manor O, Lovejoy J, Omenn GS, Hood L, Gibbons SM, Price ND. Wilmanski T, et al. Among authors: earls jc. Nat Biotechnol. 2019 Oct;37(10):1217-1228. doi: 10.1038/s41587-019-0233-9. Epub 2019 Sep 2. Nat Biotechnol. 2019. PMID: 31477923
142 results