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Protocol of DREAM3R: DuRvalumab with chEmotherapy as first-line treAtment in advanced pleural Mesothelioma-a phase 3 randomised trial.
Kok PS, Forde PM, Hughes B, Sun Z, Brown C, Ramalingam S, Cook A, Lesterhuis WJ, Yip S, O'Byrne K, Pavlakis N, Brahmer J, Anagnostou V, Ford K, Fitzpatrick K, Bricker A, Cummins MM, Stockler M, Nowak AK; Thoracic Oncology Group of Australasia (TOGA) and PrECOG, USA. Kok PS, et al. Among authors: lesterhuis wj. BMJ Open. 2022 Jan 25;12(1):e057663. doi: 10.1136/bmjopen-2021-057663. BMJ Open. 2022. PMID: 35078853 Free PMC article.
Chemoimmunotherapy: still waiting for the magic to happen.
Nowak AK, Lesterhuis WJ. Nowak AK, et al. Among authors: lesterhuis wj. Lancet Oncol. 2014 Jul;15(8):780-1. doi: 10.1016/S1470-2045(14)70267-0. Epub 2014 Jun 19. Lancet Oncol. 2014. PMID: 24954779 No abstract available.
Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy.
Principe N, Kidman J, Goh S, Tilsed CM, Fisher SA, Fear VS, Forbes CA, Zemek RM, Chopra A, Watson M, Dick IM, Boon L, Holt RA, Lake RA, Nowak AK, Lesterhuis WJ, McDonnell AM, Chee J. Principe N, et al. Among authors: lesterhuis wj. Front Immunol. 2020 Nov 12;11:584423. doi: 10.3389/fimmu.2020.584423. eCollection 2020. Front Immunol. 2020. PMID: 33262762 Free PMC article.
Malignant Pleural Effusions-A Window Into Local Anti-Tumor T Cell Immunity?
Principe N, Kidman J, Lake RA, Lesterhuis WJ, Nowak AK, McDonnell AM, Chee J. Principe N, et al. Among authors: lesterhuis wj. Front Oncol. 2021 Apr 27;11:672747. doi: 10.3389/fonc.2021.672747. eCollection 2021. Front Oncol. 2021. PMID: 33987104 Free PMC article. Review.
Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations.
Principe N, Aston WJ, Hope DE, Tilsed CM, Fisher SA, Boon L, Dick IM, Chin WL, McDonnell AM, Nowak AK, Lake RA, Chee J, Lesterhuis WJ. Principe N, et al. Among authors: lesterhuis wj. Front Immunol. 2022 May 11;13:872295. doi: 10.3389/fimmu.2022.872295. eCollection 2022. Front Immunol. 2022. PMID: 35634282 Free PMC article.
CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy.
Tilsed CM, Principe N, Kidman J, Chin WL, Orozco Morales ML, Zemek RM, Chee J, Islam R, Fear VS, Forbes C, Aston WJ, Jansen M, Chopra A, Lassmann T, Nowak AK, Fisher SA, Lake RA, Lesterhuis WJ. Tilsed CM, et al. Among authors: lesterhuis wj. Cell Rep. 2022 Dec 27;41(13):111874. doi: 10.1016/j.celrep.2022.111874. Cell Rep. 2022. PMID: 36577370 Free article.
80 results