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Page 1
Electrochemical Synthesis of Isoxazolines: Method and Mechanism.
Holman SDL, Wills AG, Fazakerley NJ, Poole DL, Coe DM, Berlouis LA, Reid M. Holman SDL, et al. Among authors: fazakerley nj. Chemistry. 2022 Mar 1;28(13):e202103728. doi: 10.1002/chem.202103728. Epub 2022 Feb 10. Chemistry. 2022. PMID: 35076117 Free PMC article.
Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
Wellaway CR, Baldwin IR, Bamborough P, Barker D, Bartholomew MA, Chung CW, Dümpelfeld B, Evans JP, Fazakerley NJ, Homes P, Keeling SP, Lewell XQ, McNab FW, Morley J, Needham D, Neu M, van Oosterhout AJM, Pal A, Reinhard FBM, Rianjongdee F, Robertson CM, Rowland P, Shah RR, Sherriff EB, Sloan LA, Teague S, Thomas DA, Wellaway N, Wojno-Picon J, Woolven JM, Coe DM. Wellaway CR, et al. Among authors: fazakerley nj. J Med Chem. 2022 Jan 13;65(1):633-664. doi: 10.1021/acs.jmedchem.1c01765. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34928601
Total synthesis of (+)-pleuromutilin.
Fazakerley NJ, Helm MD, Procter DJ. Fazakerley NJ, et al. Chemistry. 2013 May 17;19(21):6718-23. doi: 10.1002/chem.201300968. Epub 2013 Apr 15. Chemistry. 2013. PMID: 23589420
Mechanistic Basis of the Cu(OAc)2 Catalyzed Azide-Ynamine (3 + 2) Cycloaddition Reaction.
Bunschoten RP, Peschke F, Taladriz-Sender A, Alexander E, Andrews MJ, Kennedy AR, Fazakerley NJ, Lloyd Jones GC, Watson AJB, Burley GA. Bunschoten RP, et al. Among authors: fazakerley nj. J Am Chem Soc. 2024 May 15;146(19):13558-13570. doi: 10.1021/jacs.4c03348. Epub 2024 May 7. J Am Chem Soc. 2024. PMID: 38712910 Free PMC article.
A general electron transfer reduction of lactones using SmI2-H2O.
Szostak M, Collins KD, Fazakerley NJ, Spain M, Procter DJ. Szostak M, et al. Among authors: fazakerley nj. Org Biomol Chem. 2012 Aug 14;10(30):5820-4. doi: 10.1039/c2ob00017b. Epub 2012 Feb 27. Org Biomol Chem. 2012. PMID: 22367284
Cross-coupling reactions using samarium(II) iodide.
Szostak M, Fazakerley NJ, Parmar D, Procter DJ. Szostak M, et al. Among authors: fazakerley nj. Chem Rev. 2014 Jun 11;114(11):5959-6039. doi: 10.1021/cr400685r. Epub 2014 Apr 23. Chem Rev. 2014. PMID: 24758360 No abstract available.