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Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death.
Margreiter MA, Witzenberger M, Wasser Y, Davydova E, Janowski R, Metz J, Habib P, Sahnoun SEM, Sobisch C, Poma B, Palomino-Hernandez O, Wagner M, Carell T, Jon Shah N, Schulz JB, Niessing D, Voigt A, Rossetti G. Margreiter MA, et al. Among authors: voigt a. Comput Struct Biotechnol J. 2021 Dec 28;20:443-458. doi: 10.1016/j.csbj.2021.12.029. eCollection 2022. Comput Struct Biotechnol J. 2021. PMID: 35070167 Free PMC article.
TDP-43-mediated neuron loss in vivo requires RNA-binding activity.
Voigt A, Herholz D, Fiesel FC, Kaur K, Müller D, Karsten P, Weber SS, Kahle PJ, Marquardt T, Schulz JB. Voigt A, et al. PLoS One. 2010 Aug 18;5(8):e12247. doi: 10.1371/journal.pone.0012247. PLoS One. 2010. PMID: 20806063 Free PMC article.
Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia.
Reich A, Spering C, Gertz K, Harms C, Gerhardt E, Kronenberg G, Nave KA, Schwab M, Tauber SC, Drinkut A, Harms K, Beier CP, Voigt A, Göbbels S, Endres M, Schulz JB. Reich A, et al. Among authors: voigt a. J Neurosci. 2011 Jan 5;31(1):225-33. doi: 10.1523/JNEUROSCI.2188-10.2011. J Neurosci. 2011. PMID: 21209208 Free PMC article.
The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity.
Butler EK, Voigt A, Lutz AK, Toegel JP, Gerhardt E, Karsten P, Falkenburger B, Reinartz A, Winklhofer KF, Schulz JB. Butler EK, et al. Among authors: voigt a. PLoS Genet. 2012 Feb;8(2):e1002488. doi: 10.1371/journal.pgen.1002488. Epub 2012 Feb 2. PLoS Genet. 2012. PMID: 22319455 Free PMC article.
TRAP1 rescues PINK1 loss-of-function phenotypes.
Zhang L, Karsten P, Hamm S, Pogson JH, Müller-Rischart AK, Exner N, Haass C, Whitworth AJ, Winklhofer KF, Schulz JB, Voigt A. Zhang L, et al. Among authors: voigt a. Hum Mol Genet. 2013 Jul 15;22(14):2829-41. doi: 10.1093/hmg/ddt132. Epub 2013 Mar 21. Hum Mol Genet. 2013. PMID: 23525905 Free PMC article.
547 results