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Gene of the month: lymphocyte-activation gene 3 (LAG-3).
Lythgoe MP, Liu DSK, Annels NE, Krell J, Frampton AE. Lythgoe MP, et al. Among authors: annels ne. J Clin Pathol. 2021 Sep;74(9):543-547. doi: 10.1136/jclinpath-2021-207517. Epub 2021 Jun 28. J Clin Pathol. 2021. PMID: 34183437 Review.
Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer.
Simpson GR, Horvath A, Annels NE, Pencavel T, Metcalf S, Seth R, Peschard P, Price T, Coffin RS, Mostafid H, Melcher AA, Harrington KJ, Pandha HS. Simpson GR, et al. Among authors: annels ne. Br J Cancer. 2012 Jan 31;106(3):496-507. doi: 10.1038/bjc.2011.577. Epub 2012 Jan 12. Br J Cancer. 2012. PMID: 22240799 Free PMC article.
Rationale and design of the POLEM trial: avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III mismatch repair deficient or POLE exonuclease domain mutant colon cancer: a phase III randomised study.
Lau D, Kalaitzaki E, Church DN, Pandha H, Tomlinson I, Annels N, Gerlinger M, Sclafani F, Smith G, Begum R, Crux R, Gillbanks A, Wordsworth S, Chau I, Starling N, Cunningham D, Dhillon T. Lau D, et al. ESMO Open. 2020 Feb;5(1):e000638. doi: 10.1136/esmoopen-2019-000638. ESMO Open. 2020. PMID: 32079623 Free PMC article. Clinical Trial.
Phase I Trial of an ICAM-1-Targeted Immunotherapeutic-Coxsackievirus A21 (CVA21) as an Oncolytic Agent Against Non Muscle-Invasive Bladder Cancer.
Annels NE, Mansfield D, Arif M, Ballesteros-Merino C, Simpson GR, Denyer M, Sandhu SS, Melcher AA, Harrington KJ, Davies B, Au G, Grose M, Bagwan I, Fox B, Vile R, Mostafid H, Shafren D, Pandha HS. Annels NE, et al. Clin Cancer Res. 2019 Oct 1;25(19):5818-5831. doi: 10.1158/1078-0432.CCR-18-4022. Epub 2019 Jul 4. Clin Cancer Res. 2019. PMID: 31273010 Clinical Trial.
HOX and PBX gene dysregulation as a therapeutic target in glioblastoma multiforme.
Arunachalam E, Rogers W, Simpson GR, Möller-Levet C, Bolton G, Ismael M, Smith C, Keegen K, Bagwan I, Brend T, Short SC, Hong B, Otani Y, Kaur B, Annels N, Morgan R, Pandha H. Arunachalam E, et al. BMC Cancer. 2022 Apr 13;22(1):400. doi: 10.1186/s12885-022-09466-8. BMC Cancer. 2022. PMID: 35418059 Free PMC article.
46 results