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Bifunctional Opioid/Melanocortin Peptidomimetics for Use in Neuropathic Pain: Variation in the Type and Length of the Linker Connecting the Two Pharmacophores.
Witkowska E, Godlewska M, Osiejuk J, Gątarz S, Wileńska B, Kosińska K, Starnowska-Sokół J, Piotrowska A, Lipiński PFJ, Matalińska J, Dyniewicz J, Halik PK, Gniazdowska E, Przewlocka B, Misicka A. Witkowska E, et al. Among authors: starnowska sokol j. Int J Mol Sci. 2022 Jan 8;23(2):674. doi: 10.3390/ijms23020674. Int J Mol Sci. 2022. PMID: 35054860 Free PMC article.
Novel hybrid compounds, opioid agonist+melanocortin 4 receptor antagonist, as efficient analgesics in mouse chronic constriction injury model of neuropathic pain.
Starnowska-Sokół J, Piotrowska A, Bogacka J, Makuch W, Mika J, Witkowska E, Godlewska M, Osiejuk J, Gątarz S, Misicka A, Przewłocka B. Starnowska-Sokół J, et al. Neuropharmacology. 2020 Nov 1;178:108232. doi: 10.1016/j.neuropharm.2020.108232. Epub 2020 Aug 1. Neuropharmacology. 2020. PMID: 32750445 Free article.
Novel bifunctional hybrid compounds designed to enhance the effects of opioids and antagonize the pronociceptive effects of nonopioid peptides as potent analgesics in a rat model of neuropathic pain.
Piotrowska A, Starnowska-Sokół J, Makuch W, Mika J, Witkowska E, Tymecka D, Ignaczak A, Wilenska B, Misicka A, Przewłocka B. Piotrowska A, et al. Among authors: starnowska sokol j. Pain. 2021 Feb 1;162(2):432-445. doi: 10.1097/j.pain.0000000000002045. Pain. 2021. PMID: 32826750 Free PMC article.
Neuropathic Pain Dysregulates Gene Expression of the Forebrain Opioid and Dopamine Systems.
Wawrzczak-Bargieła A, Ziółkowska B, Piotrowska A, Starnowska-Sokół J, Rojewska E, Mika J, Przewłocka B, Przewłocki R. Wawrzczak-Bargieła A, et al. Among authors: starnowska sokol j. Neurotox Res. 2020 Apr;37(4):800-814. doi: 10.1007/s12640-020-00166-4. Epub 2020 Feb 5. Neurotox Res. 2020. PMID: 32026358 Free PMC article.